CERK Antibody (PACO48870)
- SKU:
- PACO48870
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | CERK Antibody (PACO48870) |
抗体コード: | PACO48870 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC, IF |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200 |
反応性: | Human, Mouse |
免疫原: | Recombinant Human Ceramide kinase protein (212-478AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Western Blot. Positive WB detected in: Mouse heart tissue, Mouse lung tissue, Mouse kidney tissue. All lanes: CERK antibody at 3µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 60, 38 kDa Observed band size: 60, 48 kDa . | |
Immunohistochemistry of paraffin-embedded human pancreatic cancer using PACO48870 at dilution of 1:100. | |
Immunohistochemistry of paraffin-embedded human colon cancer using PACO48870 at dilution of 1:100. |
バックグラウンド: | Catalyzes specifically the phosphorylation of ceramide to form ceramide 1-phosphate. Acts efficiently on natural and analog ceramides (C6, C8, C16 ceramides, and C8-dihydroceramide), to a lesser extent on C2-ceramide and C6-dihydroceramide, but not on other lipids, such as various sphingosines. Binds phosphoinositides. |
シノニム: | Ceramide kinase (hCERK) (EC 2.7.1.138) (Acylsphingosine kinase) (Lipid kinase 4) (LK4), CERK, KIAA1646 |
UniProt Protein Function: | CERK: Catalyzes specifically the phosphorylation of ceramide to form ceramide 1-phosphate. Acts efficiently on natural and analog ceramides (C6, C8, C16 ceramides, and C8-dihydroceramide), to a lesser extent on C2-ceramide and C6-dihydroceramide, but not on other lipids, such as various sphingosines. Binds phosphoinositides. |
UniProt Protein Details: | Protein type:EC 2.7.1.138; Kinase, lipid; Lipid Metabolism - sphingolipid Chromosomal Location of Human Ortholog: 22q13.31 Cellular Component: integral to membrane; plasma membrane Molecular Function:ceramide kinase activity; magnesium ion binding; protein binding Biological Process: ceramide metabolic process; glycosphingolipid metabolic process |
NCBI Summary: | CERK converts ceramide to ceramide 1-phosphate (C1P), a sphingolipid metabolite. Both CERK and C1P have been implicated in various cellular processes, including proliferation, apoptosis, phagocytosis, and inflammation (Kim et al., 2006 [PubMed 16488390]).[supplied by OMIM, Mar 2008] |
UniProt Code: | Q8TCT0 |
NCBI GenInfo Identifier: | 30172885 |
NCBI Gene ID: | 64781 |
NCBI Accession: | Q8TCT0.1 |
UniProt Secondary Accession: | Q8TCT0,Q6NX59, Q9BYB3, Q9UGE5, A0JNT4, A8K611, |
UniProt Related Accession: | Q8TCT0 |
Molecular Weight: | 60kDa |
NCBI Full Name: | Ceramide kinase |
NCBI Synonym Full Names: | ceramide kinase |
NCBI Official Symbol: | CERK |
NCBI Official Synonym Symbols: | LK4; hCERK; dA59H18.2; dA59H18.3 |
NCBI Protein Information: | ceramide kinase |
UniProt Protein Name: | Ceramide kinase |
UniProt Synonym Protein Names: | Acylsphingosine kinase; Lipid kinase 4; LK4 |
Protein Family: | Ceramide kinase |
UniProt Gene Name: | CERK |
Antibodies | ELISA Kits |
Anti-CERK Antibody (CAB15889) | Human Ceramide kinase / CERK ELISA Kit |
Human Ceramide kinase (CERK) ELISA Kit |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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