CERK Antibody (PACO15771)
- SKU:
- PACO15771
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | CERK Antibody (PACO15771) |
抗体コード: | PACO15771 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:2000-1:5000, IHC:1:25-1:100 |
反応性: | Human, Mouse |
免疫原: | Fusion protein of human CERK |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO15771(CERK Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: x200). |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human tonsil tissue using PACO15771(CERK Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: x200). |
バックグラウンド: | CERK converts ceramide to ceramide 1-phosphate (C1P), a sphingolipid metabolite. Both CERK and C1P have been implicated in various cellular processes, including proliferation, apoptosis, phagocytosis, and inflammation. Catalyzes specifically the phosphorylation of ceramide to form ceramide 1-phosphate. Acts efficiently on natural and analog ceramides (C6, C8, C16 ceramides, and C8-dihydroceramide), to a lesser extent on C2-ceramide and C6-dihydroceramide, but not on other lipids, such as various sphingosines. Binds phosphoinositides. |
シノニム: | ceramide kinase |
UniProt Protein Function: | CERK: Catalyzes specifically the phosphorylation of ceramide to form ceramide 1-phosphate. Acts efficiently on natural and analog ceramides (C6, C8, C16 ceramides, and C8-dihydroceramide), to a lesser extent on C2-ceramide and C6-dihydroceramide, but not on other lipids, such as various sphingosines. Binds phosphoinositides. |
UniProt Protein Details: | Protein type:EC 2.7.1.138; Kinase, lipid; Lipid Metabolism - sphingolipid Chromosomal Location of Human Ortholog: 22q13.31 Cellular Component: integral to membrane; plasma membrane Molecular Function:ceramide kinase activity; magnesium ion binding; protein binding Biological Process: ceramide metabolic process; glycosphingolipid metabolic process |
NCBI Summary: | CERK converts ceramide to ceramide 1-phosphate (C1P), a sphingolipid metabolite. Both CERK and C1P have been implicated in various cellular processes, including proliferation, apoptosis, phagocytosis, and inflammation (Kim et al., 2006 [PubMed 16488390]).[supplied by OMIM, Mar 2008] |
UniProt Code: | Q8TCT0 |
NCBI GenInfo Identifier: | 30172885 |
NCBI Gene ID: | 64781 |
NCBI Accession: | Q8TCT0.1 |
UniProt Secondary Accession: | Q8TCT0,Q6NX59, Q9BYB3, Q9UGE5, A0JNT4, A8K611, |
UniProt Related Accession: | Q8TCT0 |
Molecular Weight: | 60kDa |
NCBI Full Name: | Ceramide kinase |
NCBI Synonym Full Names: | ceramide kinase |
NCBI Official Symbol: | CERK |
NCBI Official Synonym Symbols: | LK4; hCERK; dA59H18.2; dA59H18.3 |
NCBI Protein Information: | ceramide kinase |
UniProt Protein Name: | Ceramide kinase |
UniProt Synonym Protein Names: | Acylsphingosine kinase; Lipid kinase 4; LK4 |
Protein Family: | Ceramide kinase |
UniProt Gene Name: | CERK |
Antibodies | ELISA Kits |
Anti-CERK Antibody (CAB15889) | Human Ceramide kinase / CERK ELISA Kit |
Human Ceramide kinase (CERK) ELISA Kit |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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