CENPH Antibody (PACO16003)
- SKU:
- PACO16003
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | CENPH Antibody (PACO16003) |
抗体コード: | PACO16003 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB |
推奨される希釈: | ELISA:1:1000-1:2000, WB:1:200-1:1000 |
反応性: | Human |
免疫原: | Fusion protein of human CENPH |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Hela cells, Primary antibody: PACO16003(CENPH Antibody) at dilution 1/250, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 second. |
バックグラウンド: | Centromere and kinetochore proteins play a critical role in centromere structure, kinetochore formation, and sister chromatid separation. The protein encoded by this gene colocalizes with inner kinetochore plate proteins CENP-A and CENP-C in both interphase and metaphase. It localizes outside of centromeric heterochromatin, where CENP-B is localized, and inside the kinetochore corona, where CENP-E is localized during prometaphase. It is thought that this protein can bind to itself, as well as to CENP-A, CENP-B or CENP-C. |
シノニム: | centromere protein H |
UniProt Protein Function: | CENPH: Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. Required for chromosome congression and efficiently align the chromosomes on a metaphase plate. Belongs to the centromere protein H family. |
UniProt Protein Details: | Protein type:Cell cycle regulation Chromosomal Location of Human Ortholog: 5p15.2 Cellular Component: cytosol; kinetochore; nucleoplasm; nucleus Molecular Function:kinetochore binding; protein binding Biological Process: DNA replication-independent nucleosome assembly at centromere; kinetochore organization and biogenesis; sister chromatid cohesion |
NCBI Summary: | Centromere and kinetochore proteins play a critical role in centromere structure, kinetochore formation, and sister chromatid separation. The protein encoded by this gene colocalizes with inner kinetochore plate proteins CENP-A and CENP-C in both interphase and metaphase. It localizes outside of centromeric heterochromatin, where CENP-B is localized, and inside the kinetochore corona, where CENP-E is localized during prometaphase. It is thought that this protein can bind to itself, as well as to CENP-A, CENP-B or CENP-C. Multimers of the protein localize constitutively to the inner kinetochore plate and play an important role in the organization and function of the active centromere-kinetochore complex. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9H3R5 |
NCBI GenInfo Identifier: | 74733576 |
NCBI Gene ID: | 64946 |
NCBI Accession: | Q9H3R5.1 |
UniProt Secondary Accession: | Q9H3R5,A8K3Y1, |
UniProt Related Accession: | Q9H3R5 |
Molecular Weight: | 28,481 Da |
NCBI Full Name: | Centromere protein H |
NCBI Synonym Full Names: | centromere protein H |
NCBI Official Symbol: | CENPH |
NCBI Protein Information: | centromere protein H |
UniProt Protein Name: | Centromere protein H |
UniProt Synonym Protein Names: | Interphase centromere complex protein 35 |
UniProt Gene Name: | CENPH |
UniProt Entry Name: | CENPH_HUMAN |
Antibodies | ELISA Kits |
Anti-CENPH Antibody (CAB8372) | Human CENPH (Centromere Protein H) ELISA Kit (HUES01840) |
CENPH Antibody (PACO08363) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |