CDH8 Antibody (PACO49458)
- SKU:
- PACO49458
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | CDH8 Antibody (PACO49458) |
抗体コード: | PACO49458 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, IF |
推奨される希釈: | ELISA:1:2000-1:10000, IF:1:50-1:200 |
反応性: | Human |
免疫原: | Recombinant Human Cadherin-8 protein (653-782AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | Immunofluorescent analysis of PC-3 cells using PACO49458 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
バックグラウンド: | Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. |
シノニム: | Cadherin-8, CDH8 |
UniProt Protein Function: | CDH8: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Cell adhesion Chromosomal Location of Human Ortholog: 16q22.1 Cellular Component: plasma membrane Biological Process: cell adhesion |
NCBI Summary: | This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is expressed in brain and is putatively involved in synaptic adhesion, axon outgrowth and guidance. [provided by RefSeq, Jul 2008] |
UniProt Code: | P55286 |
NCBI GenInfo Identifier: | 13432121 |
NCBI Gene ID: | 1006 |
NCBI Accession: | P55286.2 |
UniProt Secondary Accession: | P55286,Q14DC6, Q9ULB2, B3KWC1, |
UniProt Related Accession: | P55286 |
Molecular Weight: | 88,253 Da |
NCBI Full Name: | Cadherin-8 |
NCBI Synonym Full Names: | cadherin 8 |
NCBI Official Symbol: | CDH8 |
NCBI Official Synonym Symbols: | Nbla04261 |
NCBI Protein Information: | cadherin-8 |
UniProt Protein Name: | Cadherin-8 |
Protein Family: | Cadherin |
UniProt Gene Name: | CDH8 |
UniProt Entry Name: | CADH8_HUMAN |