CD53 Antibody (PACO45414)
- SKU:
- PACO45414
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | CD53 Antibody (PACO45414) |
抗体コード: | PACO45414 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
反応性: | Human |
免疫原: | Recombinant Human Leukocyte surface antigen CD53 protein (100-180AA) |
憲法: | Liquid |
ストレージバッファ: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
精製方法: | Antigen Affinity Purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | Immunohistochemistry of paraffin-embedded human tonsil tissue using PACO45414 at dilution of 1:100. |
![]() | Immunohistochemistry of paraffin-embedded human gastric cancer using PACO45414 at dilution of 1:100. |
バックグラウンド: | Required for efficient formation of myofibers in regenerating muscle at the level of cell fusion. May be involved in growth regulation in hematopoietic cells (By similarity). |
シノニム: | Leukocyte surface antigen CD53 (Cell surface glycoprotein CD53) (Tetraspanin-25) (Tspan-25) (CD antigen CD53), CD53, MOX44 TSPAN25 |
UniProt Protein Function: | CD53: May be involved in growth regulation in hematopoietic cells. Belongs to the tetraspanin (TM4SF) family. |
UniProt Protein Details: | Protein type:Membrane protein, multi-pass; Membrane protein, integral Chromosomal Location of Human Ortholog: 1p13 Cellular Component: cell surface; plasma membrane; integral to membrane; immunological synapse; intercellular junction Molecular Function:protein binding Biological Process: signal transduction |
NCBI Summary: | The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins. It contributes to the transduction of CD2-generated signals in T cells and natural killer cells and has been suggested to play a role in growth regulation. Familial deficiency of this gene has been linked to an immunodeficiency associated with recurrent infectious diseases caused by bacteria, fungi and viruses. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016] |
UniProt Code: | P19397 |
NCBI GenInfo Identifier: | 10834972 |
NCBI Gene ID: | 963 |
NCBI Accession: | NP_000551.1 |
UniProt Related Accession: | P19397 |
Molecular Weight: | |
NCBI Full Name: | leukocyte surface antigen CD53 isoform 1 |
NCBI Synonym Full Names: | CD53 molecule |
NCBI Official Symbol: | CD53 |
NCBI Official Synonym Symbols: | MOX44; TSPAN25 |
NCBI Protein Information: | leukocyte surface antigen CD53 |
UniProt Protein Name: | Leukocyte surface antigen CD53 |
UniProt Synonym Protein Names: | Cell surface glycoprotein CD53; Tetraspanin-25; Tspan-25; CD_antigen: CD53 |
Protein Family: | Leukocyte surface antigen |
UniProt Gene Name: | CD53 |
UniProt Entry Name: | CD53_HUMAN |