UniProt Protein Function: | IREM-1: Acts as an inhibitory receptor for myeloid cells and mast cells. Inhibits osteoclast formation. Belongs to the CD300 family. 6 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Immunoglobulin superfamily; Receptor, misc.; Membrane protein, integral Chromosomal Location of Human Ortholog: 17q25.1 Cellular Component: integral to membrane; plasma membrane Biological Process: immune system process; regulation of immune response |
NCBI Summary: | This gene encodes a member of the CD300 protein family. Members of this family are cell surface glycoproteins with a single IgV-like extracellular domain, and are involved in the regulation of immune response. The encoded protein is an inhibitory receptor. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014] |
UniProt Code: | Q8TDQ1 |
NCBI GenInfo Identifier: | 296439398 |
NCBI Gene ID: | 146722 |
NCBI Accession: | Q8TDQ1.3 |
UniProt Secondary Accession: | Q8TDQ1,Q3Y6P0, Q6UX24, Q7Z6A6, Q7Z7I4, Q7Z7I5, Q8N6D0 Q8NAF5, B2RCL2, C9JDN3, |
UniProt Related Accession: | Q8TDQ1 |
Molecular Weight: | 32,628 Da |
NCBI Full Name: | CMRF35-like molecule 1 |
NCBI Synonym Full Names: | CD300 molecule like family member f |
NCBI Official Symbol: | CD300LF |
NCBI Official Synonym Symbols: | CLM1; NKIR; CLM-1; IREM1; LMIR3; CD300f; IREM-1; IgSF13 |
NCBI Protein Information: | CMRF35-like molecule 1 |
UniProt Protein Name: | CMRF35-like molecule 1 |
UniProt Synonym Protein Names: | CD300 antigen-like family member F; Immune receptor expressed on myeloid cells 1; IREM-1; Immunoglobulin superfamily member 13; IgSF13; NK inhibitory receptor; CD_antigen: CD300f |
Protein Family: | CMRF35-like molecule |
UniProt Gene Name: | CD300LF |
UniProt Entry Name: | CLM1_HUMAN |