CCT8 Antibody, HRP conjugated (PACO47331)
- SKU:
- PACO47331
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | CCT8 Antibody, HRP conjugated (PACO47331) |
抗体コード: | PACO47331 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human T-complex protein 1 subunit theta protein (224-491AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin. |
シノニム: | T-complex protein 1 subunit theta (TCP-1-theta) (CCT-theta) (Chaperonin containing T-complex polypeptide 1 subunit 8) (Renal carcinoma antigen NY-REN-15), CCT8, C21orf112 CCTQ KIAA0002 |
UniProt Protein Function: | CCT8: a chaperone of the TCP-1 chaperonin family. A part of a hetero-oligomeric complex of about 850 to 900 kDa that forms two stacked rings, 12 to 16 nm in diameter. |
UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; Chaperone Chromosomal Location of Human Ortholog: 21q22.11 Cellular Component: centrosome; chaperonin-containing T-complex; cytoplasm; cytosol; intermediate filament cytoskeleton; microtubule; nucleoplasm Molecular Function:ATPase activity, coupled; protein binding Biological Process: positive regulation of telomere maintenance via telomerase; protein folding; protein stabilization |
NCBI Summary: | This gene encodes the theta subunit of the CCT chaperonin, which is abundant in the eukaryotic cytosol and may be involved in the transport and assembly of newly synthesized proteins. Alternative splicing results in multiple transcript variants of this gene. A pseudogene related to this gene is located on chromosome 1. [provided by RefSeq, Sep 2013] |
UniProt Code: | P50990 |
NCBI GenInfo Identifier: | 9988062 |
NCBI Gene ID: | 10694 |
NCBI Accession: | P50990.4 |
UniProt Secondary Accession: | P50990,Q4VBP8, A6NN54, B4DEM7, B4DQH4, |
UniProt Related Accession: | P50990 |
Molecular Weight: | 51,586 Da |
NCBI Full Name: | T-complex protein 1 subunit theta |
NCBI Synonym Full Names: | chaperonin containing TCP1 subunit 8 |
NCBI Official Symbol: | CCT8 |
NCBI Official Synonym Symbols: | Cctq; PRED71; D21S246; C21orf112 |
NCBI Protein Information: | T-complex protein 1 subunit theta |
UniProt Protein Name: | T-complex protein 1 subunit theta |
UniProt Synonym Protein Names: | CCT-theta; Renal carcinoma antigen NY-REN-15 |
Protein Family: | Probable T-complex protein |
UniProt Gene Name: | CCT8 |
UniProt Entry Name: | TCPQ_HUMAN |