CCR6 Antibody, Biotin conjugated (PACO25579)
- SKU:
- PACO25579
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- Biotin
Frequently bought together:
Description
抗体名: | CCR6 Antibody, Biotin conjugated (PACO25579) |
抗体コード: | PACO25579 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human C-C chemokine receptor type 6 protein (322-374AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Biotin |
バックグラウンド: | Receptor for a C-C type chemokine. Binds to MIP-3-alpha/LARC and subsequently transduces a signal by increasing the intracellular calcium ions level. |
シノニム: | C-C chemokine receptor type 6 (C-C CKR-6) (CC-CKR-6) (CCR-6) (Chemokine receptor-like 3) (CKR-L3) (DRY6) (G-protein coupled receptor 29) (GPR-CY4) (GPRCY4) (LARC receptor) (CD antigen CD196), CCR6, CKRL3 CMKBR6 GPR29 STRL22 |
UniProt Protein Function: | CCR6: Receptor for a C-C type chemokine. Binds to MIP-3- alpha/LARC and subsequently transduces a signal by increasing the intracellular calcium ions level. Belongs to the G-protein coupled receptor 1 family. |
UniProt Protein Details: | Protein type:Receptor, GPCR; Membrane protein, integral; Motility/polarity/chemotaxis; GPCR, family 1; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 6q27 Cellular Component: cell surface; cytosol; integral to plasma membrane; plasma membrane Molecular Function:C-C chemokine receptor activity; chemokine receptor activity; receptor activity Biological Process: cell motility; cellular defense response; chemotaxis; dendritic cell chemotaxis; elevation of cytosolic calcium ion concentration; G-protein coupled receptor protein signaling pathway; humoral immune response; immune response; innate immune response; signal transduction |
NCBI Summary: | This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq, Jul 2008] |
UniProt Code: | P51684 |
NCBI GenInfo Identifier: | 2851567 |
NCBI Gene ID: | 1235 |
NCBI Accession: | P51684.2 |
UniProt Secondary Accession: | P51684,P78553, Q92846, E1P5C6, |
UniProt Related Accession: | P51684 |
Molecular Weight: | 42,494 Da |
NCBI Full Name: | C-C chemokine receptor type 6 |
NCBI Synonym Full Names: | C-C motif chemokine receptor 6 |
NCBI Official Symbol: | CCR6 |
NCBI Official Synonym Symbols: | BN-1; DCR2; DRY6; CCR-6; CD196; CKRL3; GPR29; CKR-L3; CMKBR6; GPRCY4; STRL22; CC-CKR-6; C-C CKR-6 |
NCBI Protein Information: | C-C chemokine receptor type 6 |
UniProt Protein Name: | C-C chemokine receptor type 6 |
UniProt Synonym Protein Names: | Chemokine receptor-like 3; CKR-L3; DRY6; G-protein coupled receptor 29; GPR-CY4; GPRCY4; LARC receptor; CD_antigen: CD196 |
Protein Family: | C-C chemokine receptor |
UniProt Gene Name: | CCR6 |
UniProt Entry Name: | CCR6_HUMAN |