Ccl4 Antibody, HRP conjugated (PACO32657)
- SKU:
- PACO32657
- Product type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | Ccl4 Antibody, HRP conjugated (PACO32657) |
抗体コード: | PACO32657 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Mouse |
免疫原: | Recombinant Mouse C-C motif chemokine 4 protein (24-92AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | Monokine with inflammatory and chemokinetic properties. |
シノニム: | C-C motif chemokine 4 (Immune activation protein 2) (ACT-2) (ACT2) (Macrophage inflammatory protein 1-beta) (MIP-1-beta) (Protein H400) (SIS-gamma) (Small-inducible cytokine A4), Ccl4, Mip1b Scya4 |
UniProt Protein Function: | CCL4: Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5- mediated entry of HIV-1 in T-cells. MIP-1-beta(3-69) is also a ligand for CCR1 and CCR2 isoform B. Belongs to the intercrine beta (chemokine CC) family. |
UniProt Protein Details: | Protein type:Secreted; Chemokine; Motility/polarity/chemotaxis; Secreted, signal peptide Cellular Component: extracellular space; extracellular region Molecular Function:identical protein binding; protein binding; CCR1 chemokine receptor binding; chemokine activity; cytokine activity; CCR5 chemokine receptor binding Biological Process: leukocyte chemotaxis; response to toxin; immune response; positive regulation of calcium-mediated signaling; positive regulation of tumor necrosis factor production; inflammatory response; chemotaxis; positive regulation of calcium ion transport; positive regulation of vascular permeability |
UniProt Code: | P14097 |
NCBI GenInfo Identifier: | 1346534 |
NCBI Gene ID: | 20303 |
NCBI Accession: | P14097.3 |
UniProt Related Accession: | P14097 |
Molecular Weight: | 10,168 Da |
NCBI Full Name: | C-C motif chemokine 4 |
NCBI Synonym Full Names: | chemokine (C-C motif) ligand 4 |
NCBI Official Symbol: | Ccl4 |
NCBI Official Synonym Symbols: | Act-2; Mip1b; Scya4; MIP-1B; AT744.1 |
NCBI Protein Information: | C-C motif chemokine 4; ACT2; SIS-gamma; MIP-1 beta; MIP-1-beta; immune activation protein 2; small inducible cytokine A4; small-inducible cytokine A4; macrophage inflammatory protein 1-beta |
UniProt Protein Name: | C-C motif chemokine 4 |
UniProt Synonym Protein Names: | Immune activation protein 2; ACT-2; ACT2; Macrophage inflammatory protein 1-beta; MIP-1-beta; Protein H400; SIS-gamma; Small-inducible cytokine A4 |
Protein Family: | C-C motif chemokine |
UniProt Gene Name: | Ccl4 |
UniProt Entry Name: | CCL4_MOUSE |