CCL21 Antibody, Biotin conjugated (PACO25551)
- SKU:
- PACO25551
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- Biotin
Frequently bought together:
Description
抗体名: | CCL21 Antibody, Biotin conjugated (PACO25551) |
抗体コード: | PACO25551 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human C-C motif chemokine 21 protein (24-134AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Biotin |
バックグラウンド: | Inhibits hemopoiesis and stimulates chemotaxis. Chemotactic in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Shows preferential activity towards naive T-cells. May play a role in mediating homing of lymphocytes to secondary lymphoid organs. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4. |
シノニム: | C-C motif chemokine 21 (6Ckine) (Beta-chemokine exodus-2) (Secondary lymphoid-tissue chemokine) (SLC) (Small-inducible cytokine A21), CCL21, SCYA21 |
NCBI Summary: | This antimicrobial gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. Similar to other chemokines the protein encoded by this gene inhibits hemopoiesis and stimulates chemotaxis. This protein is chemotactic in vitro for thymocytes and activated T cells, but not for B cells, macrophages, or neutrophils. The cytokine encoded by this gene may also play a role in mediating homing of lymphocytes to secondary lymphoid organs. It is a high affinity functional ligand for chemokine receptor 7 that is expressed on T and B lymphocytes and a known receptor for another member of the cytokine family (small inducible cytokine A19). [provided by RefSeq, Sep 2014] |
UniProt Code: | O00585 |
NCBI GenInfo Identifier: | 6094386 |
NCBI Gene ID: | 6366 |
NCBI Accession: | O00585.1 |
UniProt Related Accession: | O00585 |
Molecular Weight: | |
NCBI Full Name: | C-C motif chemokine 21 |
NCBI Synonym Full Names: | C-C motif chemokine ligand 21 |
NCBI Official Symbol: | CCL21 |
NCBI Official Synonym Symbols: | ECL; SLC; CKb9; TCA4; 6Ckine; SCYA21 |
NCBI Protein Information: | C-C motif chemokine 21 |
UniProt Protein Name: | C-C motif chemokine 21 |
UniProt Synonym Protein Names: | 6Ckine; Beta-chemokine exodus-2; Secondary lymphoid-tissue chemokine; SLC; Small-inducible cytokine A21 |
Protein Family: | C-C motif chemokine |
UniProt Gene Name: | CCL21 |
UniProt Entry Name: | CCL21_HUMAN |