CCL17 Antibody, Biotin conjugated (PACO55253)
- SKU:
- PACO55253
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- Biotin
Frequently bought together:
Description
抗体名: | CCL17 Antibody, Biotin conjugated (PACO55253) |
抗体コード: | PACO55253 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human C-C motif chemokine 17 protein (24-94AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Biotin |
バックグラウンド: | Chemotactic factor for T-lymphocytes but not monocytes or granulocytes. May play a role in T-cell development in thymus and in trafficking and activation of mature T-cells. Binds to CCR4. |
シノニム: | C-C motif chemokine 17 (CC chemokine TARC) (Small-inducible cytokine A17) (Thymus and activation-regulated chemokine), CCL17, SCYA17 TARC |
UniProt Protein Function: | CCL17: Chemotactic factor for T-lymphocytes but not monocytes or granulocytes. May play a role in T-cell development in thymus and in trafficking and activation of mature T-cells. Binds to CCR4. Belongs to the intercrine beta (chemokine CC) family. |
UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 16q13 Cellular Component: extracellular space; extracellular region Molecular Function:CCR4 chemokine receptor binding; chemokine activity; receptor binding Biological Process: G-protein coupled receptor protein signaling pathway; cell-cell signaling; multicellular organismal development; immune response; chemotaxis; inflammatory response; negative regulation of myoblast differentiation |
NCBI Summary: | This antimicrobial gene is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 16. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity for T lymphocytes, but not monocytes or granulocytes. The product of this gene binds to chemokine receptors CCR4 and CCR8. This chemokine plays important roles in T cell development in thymus as well as in trafficking and activation of mature T cells. [provided by RefSeq, Sep 2014] |
UniProt Code: | Q92583 |
NCBI GenInfo Identifier: | 3024711 |
NCBI Gene ID: | 6361 |
NCBI Accession: | Q92583.1 |
UniProt Secondary Accession: | Q92583,Q2M287, A0N0Q9, |
UniProt Related Accession: | Q92583 |
Molecular Weight: | 10,507 Da |
NCBI Full Name: | C-C motif chemokine 17 |
NCBI Synonym Full Names: | chemokine (C-C motif) ligand 17 |
NCBI Official Symbol: | CCL17 |
NCBI Official Synonym Symbols: | TARC; ABCD-2; SCYA17; A-152E5.3 |
NCBI Protein Information: | C-C motif chemokine 17; CC chemokine TARC; T cell-directed CC chemokine; small-inducible cytokine A17; thymus and activation-regulated chemokine; small inducible cytokine subfamily A (Cys-Cys), member 17 |
UniProt Protein Name: | C-C motif chemokine 17 |
UniProt Synonym Protein Names: | CC chemokine TARC; Small-inducible cytokine A17; Thymus and activation-regulated chemokine |
UniProt Gene Name: | CCL17 |
UniProt Entry Name: | CCL17_HUMAN |