CCK Antibody (PACO05632)
- SKU:
- PACO05632
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Description
抗体名: | CCK Antibody (PACO05632) |
抗体コード: | PACO05632 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:20000, IHC:1:100-1:300 |
反応性: | Human, Mouse, Rat |
免疫原: | Synthesized peptide derived from the Internal region of human CCK. |
憲法: | Liquid |
ストレージバッファ: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | CCK; Cholecystokinin; CCK |
UniProt Protein Function: | CCK: This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion. Belongs to the gastrin/cholecystokinin family. |
UniProt Protein Details: | Protein type:Secreted; Hormone; Secreted, signal peptide; Cell development/differentiation Chromosomal Location of Human Ortholog: 3p22.1 Cellular Component: axon; axon hillock; dendrite; extracellular region; extracellular space; perikaryon; terminal button Molecular Function:hormone activity; neuropeptide hormone activity; protein binding Biological Process: axonogenesis; behavioral fear response; caspase activation; eating behavior; negative regulation of appetite; neuron migration; positive regulation of cell proliferation; positive regulation of glutamate secretion; positive regulation of mitochondrial depolarization; positive regulation of peptidyl-tyrosine phosphorylation; positive regulation of protein oligomerization; protein kinase C activation; regulation of sensory perception of pain; release of cytochrome c from mitochondria; signal transduction |
NCBI Summary: | This gene encodes a member of the gastrin/cholecystokinin family of proteins. The encoded preproprotein is proteolytically processed to generate multiple protein products, including the peptide hormones cholecystokinin-8, -12, -33, and others. The encoded peptides have been shown to regulate gastric acid secretion and food intake. A sulfated form of cholecystokinin-8 may modulate neuronal activity in the brain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2015] |
UniProt Code: | P06307 |
NCBI GenInfo Identifier: | 115945 |
NCBI Gene ID: | 885 |
NCBI Accession: | P06307.1 |
UniProt Related Accession: | P06307 |
Molecular Weight: | 12,669 Da |
NCBI Full Name: | Cholecystokinin |
NCBI Synonym Full Names: | cholecystokinin |
NCBI Official Symbol: | CCK |
NCBI Protein Information: | cholecystokinin |
UniProt Protein Name: | Cholecystokinin |
UniProt Synonym Protein Names: | Cholecystokinin-58; CCK58 |
UniProt Gene Name: | CCK |
UniProt Entry Name: | CCKN_HUMAN |