CBX8 Antibody (PACO43137)
- SKU:
- PACO43137
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | CBX8 Antibody (PACO43137) |
抗体コード: | PACO43137 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:200-1:1000, IHC:1:20-1:200 |
反応性: | Human |
免疫原: | Recombinant Human Chromobox protein homolog 8 protein (80-280AA) |
憲法: | Liquid |
ストレージバッファ: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
精製方法: | Antigen Affinity Purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Western blot. All lanes: CBX8 antibody at 2µg/ml + Jurkat whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 43 kDa. Observed band size: 43 kDa. | |
Immunohistochemistry of paraffin-embedded human colon cancer using PACO43137 at dilution of 1:100. | |
Immunohistochemistry of paraffin-embedded human skin tissue using PACO43137 at dilution of 1:100. |
バックグラウンド: | Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. |
シノニム: | Chromobox protein homolog 8 (Polycomb 3 homolog) (Pc3) (hPc3) (Rectachrome 1), CBX8, PC3 RC1 |
UniProt Protein Function: | CBX8: Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. |
UniProt Protein Details: | Protein type:Transcription, coactivator/corepressor Chromosomal Location of Human Ortholog: 17q25.3 Cellular Component: nucleoplasm; heterochromatin; nuclear chromatin; PcG protein complex; nucleus Molecular Function:protein binding; single-stranded RNA binding; ubiquitin-protein ligase activity; methylated histone residue binding Biological Process: transcription, DNA-dependent; histone ubiquitination; negative regulation of transcription from RNA polymerase II promoter |
UniProt Code: | Q9HC52 |
NCBI GenInfo Identifier: | 78099843 |
NCBI Gene ID: | 57332 |
NCBI Accession: | Q9HC52.3 |
UniProt Secondary Accession: | Q9HC52,Q96H39, Q9NR07, |
UniProt Related Accession: | Q9HC52 |
Molecular Weight: | 389 |
NCBI Full Name: | Chromobox protein homolog 8 |
NCBI Synonym Full Names: | chromobox homolog 8 |
NCBI Official Symbol: | CBX8 |
NCBI Official Synonym Symbols: | PC3; RC1 |
NCBI Protein Information: | chromobox protein homolog 8; polycomb 3; rectachrome 1; Pc class 3 homolog; chromobox homolog 8 (Pc class homolog, Drosophila) |
UniProt Protein Name: | Chromobox protein homolog 8 |
UniProt Synonym Protein Names: | Polycomb 3 homolog; Pc3; hPc3; Rectachrome 1 |
Protein Family: | Chromobox protein |
UniProt Gene Name: | CBX8 |
UniProt Entry Name: | CBX8_HUMAN |
Antibodies |
Anti-CBX8 Antibody (CAB6222) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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