CAMK2N2 Antibody, Biotin conjugated (PACO63634)
- SKU:
- PACO63634
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- Biotin
Frequently bought together:
Description
抗体名: | CAMK2N2 Antibody, Biotin conjugated (PACO63634) |
抗体コード: | PACO63634 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Peptide sequence from Human Calcium/calmodulin-dependent protein kinase II inhibitor 2 protein (10-28AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | Antigen Affinity Purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Biotin |
バックグラウンド: | Potent and specific cellular inhibitor of CaM-kinase II (CAMK2). Traps Ca(2+)/calmodulin on CAMK2. May play an important role in the regulation of cell growth when overexpressed in colon adenocarcinoma LoVo cells. Traps Ca(2+)/calmodulin on CAMK2. |
シノニム: | Calcium/calmodulin-dependent protein kinase II inhibitor 2 (CaM-KII inhibitory protein) (CaM-KIIN), CAMK2N2 |
UniProt Protein Function: | CAMK2N2: Potent and specific cellular inhibitor of CaM-kinase II (CAMK2). Traps Ca(2+)/calmodulin on CAMK2. May play an important role in the regulation of cell growth when overexpressed in colon adenocarcinoma LoVo cells. Traps Ca(2+)/calmodulin on CAMK2. Belongs to the CAMK2N family. |
UniProt Protein Details: | Protein type:Protein kinase, regulatory subunit; Inhibitor Chromosomal Location of Human Ortholog: 3q27.1 Cellular Component: centrosome; cytosol; nucleus Molecular Function:calcium-dependent protein kinase inhibitor activity; protein kinase binding |
NCBI Summary: | This gene encodes a protein that is highly similar to the rat CaM-KII inhibitory protein, an inhibitor of calcium/calmodulin-dependent protein kinase II (CAMKII). CAMKII regulates numerous physiological functions, including neuronal synaptic plasticity through the phosphorylation of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid-type glutamate (AMPA) receptors. Studies of the similar protein in rat suggest that this protein may function as a negative regulator of CaM-KII and may act to inhibit the phosphorylation of AMPA receptors. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q96S95 |
NCBI GenInfo Identifier: | 15147234 |
NCBI Gene ID: | 94032 |
NCBI Accession: | NP_150284.1 |
UniProt Related Accession: | Q96S95 |
Molecular Weight: | 8,658 Da |
NCBI Full Name: | calcium/calmodulin-dependent protein kinase II inhibitor 2 |
NCBI Synonym Full Names: | calcium/calmodulin dependent protein kinase II inhibitor 2 |
NCBI Official Symbol: | CAMK2N2 |
NCBI Official Synonym Symbols: | CAMKIIN; CAM-KIIN |
NCBI Protein Information: | calcium/calmodulin-dependent protein kinase II inhibitor 2 |
UniProt Protein Name: | Calcium/calmodulin-dependent protein kinase II inhibitor 2 |
UniProt Synonym Protein Names: | CaM-KII inhibitory protein; CaM-KIIN |
Protein Family: | Calcium/calmodulin-dependent protein kinase II inhibitor |
UniProt Gene Name: | CAMK2N2 |
UniProt Entry Name: | CK2N2_HUMAN |