CACTIN Antibody (PACO07291)
- SKU:
- PACO07291
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | CACTIN Antibody (PACO07291) |
抗体コード: | PACO07291 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB |
推奨される希釈: | ELISA:1:10000, WB:1:500-1:10000 |
反応性: | Human, Mouse, Rat |
免疫原: | Synthetic peptide from human protein at AA range: 141-190 |
憲法: | Liquid |
ストレージバッファ: | PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. |
精製方法: | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | Western Blot analysis of hepg2 cells using Antibody diluted at 1000. Secondary antibody was diluted at 1:20000. |
シノニム: | CACTIN C19orf29 |
UniProt Protein Function: | CACTIN: Involved in the regulation of innate immune response. Acts as negative regulator of Toll-like receptor and interferon- regulatory factor (IRF) signaling pathways. Contributes to the regulation of transcriptional activation of NF-kappa-B target genes in response to endogenous proinflammatory stimuli. May play a role during early embryonic development. Probably involved in pre-mRNA splicing. Belongs to the CACTIN family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Motility/polarity/chemotaxis; Spliceosome; RNA splicingChromosomal Location of Human Ortholog: 19p13.3Cellular Component: nucleoplasm; cytoplasm; nucleusMolecular Function: protein bindingBiological Process: nuclear mRNA splicing, via spliceosome; negative regulation of lipopolysaccharide-mediated signaling pathway; negative regulation of protein amino acid phosphorylation; inhibition of NF-kappaB transcription factor; multicellular organismal development; negative regulation of toll-like receptor signaling pathway; negative regulation of interleukin-8 production; innate immune response; negative regulation of tumor necrosis factor production; negative regulation of interferon-beta production |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | Q8WUQ7 |
NCBI GenInfo Identifier: | 122937392 |
NCBI Gene ID: | 58509 |
NCBI Accession: | NP_001074012.1 |
UniProt Secondary Accession: | Q8WUQ7 |
UniProt Related Accession: | Q8WUQ7 |
Molecular Weight: | 89 kDa |
NCBI Full Name: | cactin |
NCBI Synonym Full Names: | cactin, spliceosome C complex subunit |
NCBI Official Symbol: | CACTIN |
NCBI Official Synonym Symbols: | fSAPc; C19orf29; NY-REN-24 |
NCBI Protein Information: | cactin |
UniProt Protein Name: | Cactin |
UniProt Synonym Protein Names: | Renal carcinoma antigen NY-REN-24 |
Protein Family: | Cactin |
UniProt Gene Name: | CACTIN |
UniProt Entry Name: | CATIN_HUMAN |