CACNB4 Antibody (PACO49438)
- SKU:
- PACO49438
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | CACNB4 Antibody (PACO49438) |
抗体コード: | PACO49438 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, IHC, IF |
推奨される希釈: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
反応性: | Human |
免疫原: | Recombinant Human Voltage-dependent L-type calcium channel subunit beta-4 protein (1-217AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | Immunohistochemistry of paraffin-embedded human adrenal gland tissue using PACO49438 at dilution of 1:100. |
![]() | Immunofluorescent analysis of PC-3 cells using PACO49438 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
バックグラウンド: | The β subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting. |
シノニム: | Voltage-dependent L-type calcium channel subunit beta-4 (CAB4) (Calcium channel voltage-dependent subunit β 4), CACNB4, CACNLB4 |
NCBI Summary: | This gene encodes a member of the beta subunit family of voltage-dependent calcium channel complex proteins. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. The protein encoded by this locus plays an important role in calcium channel function by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Certain mutations in this gene have been associated with idiopathic generalized epilepsy (IGE), juvenile myoclonic epilepsy (JME), and episodic ataxia, type 5. [provided by RefSeq, Aug 2016] |
UniProt Code: | O00305 |
NCBI GenInfo Identifier: | 54607064 |
NCBI Gene ID: | 785 |
NCBI Accession: | NP_000717 |
UniProt Related Accession: | O00305 |
Molecular Weight: | |
NCBI Full Name: | voltage-dependent L-type calcium channel subunit beta-4 isoform b |
NCBI Synonym Full Names: | calcium voltage-gated channel auxiliary subunit beta 4 |
NCBI Official Symbol: | CACNB4 |
NCBI Official Synonym Symbols: | EA5; EJM; CAB4; EIG9; EJM4; EJM6; CACNLB4 |
NCBI Protein Information: | voltage-dependent L-type calcium channel subunit beta-4 |
UniProt Protein Name: | Voltage-dependent L-type calcium channel subunit beta-4 |
UniProt Synonym Protein Names: | Calcium channel voltage-dependent subunit beta 4 |
UniProt Gene Name: | CACNB4 |
UniProt Entry Name: | CACB4_HUMAN |
Antibodies |
Anti-CACNB4 Antibody (CAB9304) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |