CACNA2D1 Antibody, FITC conjugated (PACO25458)
- SKU:
- PACO25458
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- FITC
Frequently bought together:
Description
抗体名: | CACNA2D1 Antibody, FITC conjugated (PACO25458) |
抗体コード: | PACO25458 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Voltage-dependent calcium channel subunit alpha-2/delta-1 protein (577-717AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | FITC |
バックグラウンド: | The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel. Plays an important role in excitation-contraction coupling. |
シノニム: | Voltage-dependent calcium channel subunit alpha-2/delta-1 (Voltage-gated calcium channel subunit alpha-2/delta-1) [Cleaved into: Voltage-dependent calcium channel subunit alpha-2-1; Voltage-dependent calcium channel subunit delta-1], CACNA2D1, CACNL2A CCHL2A MHS3 |
UniProt Protein Function: | CACNA2D1: The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel. Plays an important role in excitation-contraction coupling. Belongs to the calcium channel subunit alpha-2/delta family. 5 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Channel, calcium; Membrane protein, integral Chromosomal Location of Human Ortholog: 7q21-q22 Cellular Component: plasma membrane; voltage-gated calcium channel complex Molecular Function:voltage-gated calcium channel activity Biological Process: calcium ion transport; regulation of calcium ion transport |
NCBI Summary: | The preproprotein encoded by this gene is cleaved into multiple chains that comprise the alpha-2 and delta subunits of the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. Mutations in this gene can cause cardiac deficiencies, including Brugada syndrome and short QT syndrome. Alternate splicing results in multiple transcript variants, some of which may lack the delta subunit portion. [provided by RefSeq, Nov 2014] |
UniProt Code: | P54289 |
NCBI GenInfo Identifier: | 262527579 |
NCBI Gene ID: | 781 |
NCBI Accession: | P54289.3 |
UniProt Secondary Accession: | P54289,Q17R45, Q9UD80, Q9UD81, Q9UD82, |
UniProt Related Accession: | P54289 |
Molecular Weight: | 122,443 Da |
NCBI Full Name: | Voltage-dependent calcium channel subunit alpha-2/delta-1 |
NCBI Synonym Full Names: | calcium voltage-gated channel auxiliary subunit alpha2delta 1 |
NCBI Official Symbol: | CACNA2D1 |
NCBI Official Synonym Symbols: | CACNA2; CCHL2A; CACNL2A; LINC01112; lncRNA-N3 |
NCBI Protein Information: | voltage-dependent calcium channel subunit alpha-2/delta-1 |
UniProt Protein Name: | Voltage-dependent calcium channel subunit alpha-2/delta-1 |
UniProt Synonym Protein Names: | Voltage-gated calcium channel subunit alpha-2/delta-1 |
Protein Family: | Voltage-dependent calcium channel |
UniProt Gene Name: | CACNA2D1 |
UniProt Entry Name: | CA2D1_HUMAN |