BMP3 Antibody (PACO14139)
- SKU:
- PACO14139
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | BMP3 Antibody (PACO14139) |
抗体コード: | PACO14139 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:1000-1:2000, IHC:1:15-1:50 |
反応性: | Human, Mouse, Rat |
免疫原: | Fusion protein of human BMP3 |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO14139(BMP3 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: x200). |
バックグラウンド: | BMP3 belongs to the transforming growth factor-β (TGFB) superfamily. Bone morphogenic protein, also known as osteogenin, induces bone formation. Negatively regulates bone density. Antagonizes the ability of certain osteogenic BMPs to induce osteoprogenitor differentitation and ossification. Expressed in adult and fetal cartilage. Highly expressed in fracture tissue, particularly in osteoblasts, osteoclasts and chondroblasts. |
シノニム: | bone morphogenetic protein 3 |
UniProt Protein Function: | BMP3: Negatively regulates bone density. Antagonizes the ability of certain osteogenic BMPs to induce osteoprogenitor differentitation and ossification. Belongs to the TGF-beta family. |
UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide; Cytokine Chromosomal Location of Human Ortholog: 4q21 Cellular Component: extracellular space Molecular Function:cytokine activity; receptor binding; transforming growth factor beta receptor binding Biological Process: BMP signaling pathway; cell development; cell-cell signaling; regulation of apoptosis; regulation of MAPKKK cascade; skeletal development |
NCBI Summary: | BMP3 belongs to the transforming growth factor-beta (TGFB) superfamily. Bone morphogenic protein, also known as osteogenin, induces bone formation. [provided by RefSeq, Jul 2008] |
UniProt Code: | P12645 |
NCBI GenInfo Identifier: | 215273985 |
NCBI Gene ID: | 651 |
NCBI Accession: | P12645.2 |
UniProt Secondary Accession: | P12645,Q4VAS5, |
UniProt Related Accession: | P12645 |
Molecular Weight: | 53,372 Da |
NCBI Full Name: | Bone morphogenetic protein 3 |
NCBI Synonym Full Names: | bone morphogenetic protein 3 |
NCBI Official Symbol: | BMP3 |
NCBI Official Synonym Symbols: | BMP-3A |
NCBI Protein Information: | bone morphogenetic protein 3 |
UniProt Protein Name: | Bone morphogenetic protein 3 |
UniProt Synonym Protein Names: | Bone morphogenetic protein 3A; BMP-3A; Osteogenin |
Protein Family: | Bone morphogenetic protein |
UniProt Gene Name: | BMP3 |
UniProt Entry Name: | BMP3_HUMAN |
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