BMP2 Antibody (PACO07127)
- SKU:
- PACO07127
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | BMP2 Antibody (PACO07127) |
抗体コード: | PACO07127 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB |
推奨される希釈: | ELISA:1:10000, WB:1:500-1:2000 |
反応性: | Human, Mouse, Rat |
免疫原: | Synthesized peptide derived from the C-terminal region of human BMP-2. |
憲法: | Liquid |
ストレージバッファ: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | Western Blot analysis of HepG2-UV L929 cells using BMP-2 Polyclonal Antibody. |
![]() | Immunohistochemical analysis of paraffin-embedded human-breast-cancer, antibody was diluted at 1:200. |
![]() | Western Blot analysis of HEPG2-UV cells using BMP-2 Polyclonal Antibody. |
シノニム: | BMP2; BMP2A; Bone morphogenetic protein 2; BMP-2; Bone morphogenetic protein 2A; BMP-2A |
UniProt Protein Function: | Induces cartilage and bone formation (PubMed:3201241). Stimulates the differentiation of myoblasts into osteoblasts via the EIF2AK3-EIF2A- ATF4 pathway. BMP2 activation of EIF2AK3 stimulates phosphorylation of EIF2A which leads to increased expression of ATF4 which plays a central role in osteoblast differentiation. In addition stimulates TMEM119, which upregulates the expression of ATF4 (PubMed:24362451). |
NCBI Summary: | The protein encoded by this gene belongs to the transforming growth factor-beta (TGFB) superfamily. The encoded protein acts as a disulfide-linked homodimer and induces bone and cartilage formation. [provided by RefSeq, Jul 2008] |
UniProt Code: | P12643 |
NCBI GenInfo Identifier: | 115068 |
NCBI Gene ID: | 650 |
NCBI Accession: | P12643.1 |
UniProt Related Accession: | P12643 |
Molecular Weight: | |
NCBI Full Name: | Bone morphogenetic protein 2 |
NCBI Synonym Full Names: | bone morphogenetic protein 2 |
NCBI Official Symbol: | BMP2 |
NCBI Official Synonym Symbols: | BDA2; BMP2A |
NCBI Protein Information: | bone morphogenetic protein 2; BMP-2A; bone morphogenetic protein 2A |
UniProt Protein Name: | Bone morphogenetic protein 2 |
UniProt Synonym Protein Names: | Bone morphogenetic protein 2A; BMP-2A |
Protein Family: | Bone morphogenetic protein |
UniProt Gene Name: | BMP2 |
UniProt Entry Name: | BMP2_HUMAN |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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