BLK Antibody (PACO00468)
- SKU:
- PACO00468
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | BLK Antibody |
抗体コード: | PACO00468 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | IHC:1:100-1:300 |
反応性: | Human, Mouse, Rat |
免疫原: | synthesized peptide derived from human Blk around the non-phosphorylation site of Y501. |
憲法: | Liquid |
ストレージバッファ: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | BLK; Tyrosine-protein kinase Blk; B lymphocyte kinase; p55-Blk |
UniProt Protein Function: | BLK: a nonreceptor tyrosine kinase of the Src family. Expressed predominantly in B lymphocytes |
UniProt Protein Details: | Protein type:Protein kinase, TK; Kinase, protein; EC 2.7.10.2; Protein kinase, tyrosine (non-receptor); TK group; Src family Chromosomal Location of Human Ortholog: 8p23-p22 Cellular Component: extrinsic to internal side of plasma membrane Molecular Function:protein binding; protein-tyrosine kinase activity; non-membrane spanning protein tyrosine kinase activity; ATP binding; receptor binding Biological Process: B cell receptor signaling pathway; innate immune response; positive regulation of insulin secretion; transmembrane receptor protein tyrosine kinase signaling pathway; regulation of cell proliferation; T cell differentiation Disease: Maturity-onset Diabetes Of The Young, Type 11 |
NCBI Summary: | This gene encodes a nonreceptor tyrosine-kinase of the src family of proto-oncogenes that are typically involved in cell proliferation and differentiation. The protein has a role in B-cell receptor signaling and B-cell development. The protein also stimulates insulin synthesis and secretion in response to glucose and enhances the expression of several pancreatic beta-cell transcription factors. [provided by RefSeq, Aug 2010] |
UniProt Code: | P51451 |
NCBI GenInfo Identifier: | 158936749 |
NCBI Gene ID: | 640 |
NCBI Accession: | P51451.3 |
UniProt Secondary Accession: | P51451,Q16291, Q96IN1, |
UniProt Related Accession: | P51451 |
Molecular Weight: | 505 |
NCBI Full Name: | Tyrosine-protein kinase Blk |
NCBI Synonym Full Names: | BLK proto-oncogene, Src family tyrosine kinase |
NCBI Official Symbol: | BLK |
NCBI Official Synonym Symbols: | MODY11 |
NCBI Protein Information: | tyrosine-protein kinase Blk; p55-Blk; b lymphocyte kinase; B lymphoid tyrosine kinase; BLK nonreceptor tyrosine kinase |
UniProt Protein Name: | Tyrosine-protein kinase Blk |
UniProt Synonym Protein Names: | B lymphocyte kinase; p55-Blk |
Protein Family: | Tyrosine-protein kinase |
UniProt Gene Name: | BLK |
UniProt Entry Name: | BLK_HUMAN |