BCL3 Antibody, Biotin conjugated (PACO55409)
- SKU:
- PACO55409
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- Biotin
Frequently bought together:
Description
抗体名: | BCL3 Antibody, Biotin conjugated (PACO55409) |
抗体コード: | PACO55409 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human B-cell lymphoma 3 protein (362-454AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Biotin |
バックグラウンド: | Contributes to the regulation of transcriptional activation of NF-kappa-B target genes. In the cytoplasm, inhibits the nuclear translocation of the NF-kappa-B p50 subunit. In the nucleus, acts as transcriptional activator that promotes transcription of NF-kappa-B target genes. Contributes to the regulation of cell proliferation (By similarity). |
シノニム: | B-cell lymphoma 3 protein (BCL-3) (Proto-oncogene BCL3), BCL3, BCL4 D19S37 |
UniProt Protein Function: | Contributes to the regulation of transcriptional activation of NF-kappa-B target genes. In the cytoplasm, inhibits the nuclear translocation of the NF-kappa-B p50 subunit. In the nucleus, acts as transcriptional activator that promotes transcription of NF-kappa-B target genes. Contributes to the regulation of cell proliferation. |
NCBI Summary: | This gene is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein encoded by this gene contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers. The expression of this gene can be induced by NF-kappa B, which forms a part of the autoregulatory loop that controls the nuclear residence of p50 NF-kappa B. [provided by RefSeq, Jul 2008] |
UniProt Code: | P20749 |
NCBI GenInfo Identifier: | 294862410 |
NCBI Gene ID: | 602 |
NCBI Accession: | P20749.2 |
UniProt Related Accession: | P20749 |
Molecular Weight: | 48kDa |
NCBI Full Name: | B-cell lymphoma 3 protein |
NCBI Synonym Full Names: | B-cell CLL/lymphoma 3 |
NCBI Official Symbol: | BCL3 |
NCBI Official Synonym Symbols: | BCL4; D19S37 |
NCBI Protein Information: | B-cell lymphoma 3 protein |
UniProt Protein Name: | B-cell lymphoma 3 protein |
UniProt Synonym Protein Names: | Proto-oncogene BCL3 |
Protein Family: | B-cell lymphoma 3 protein |
UniProt Gene Name: | BCL3 |