BAMBI Antibody (PACO43359)
- SKU:
- PACO43359
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | BAMBI Antibody (PACO43359) |
抗体コード: | PACO43359 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
反応性: | Human |
免疫原: | Recombinant Human BMP and activin membrane-bound inhibitor homolog protein (21-152AA) |
憲法: | Liquid |
ストレージバッファ: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
精製方法: | Antigen Affinity purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | Immunohistochemistry of paraffin-embedded human prostate tissue using PACO43359 at dilution of 1:100. |
![]() | Immunohistochemistry of paraffin-embedded human placenta tissue using PACO43359 at dilution of 1:100. |
![]() | Immunohistochemistry of paraffin-embedded human colon tissue using PACO43359 at dilution of 1:100. |
バックグラウンド: | Negatively regulates TGF-β signaling. |
シノニム: | BMP and activin membrane-bound inhibitor homolog (Non-metastatic gene A protein) (Putative transmembrane protein NMA), BAMBI, NMA |
UniProt Protein Function: | BAMBI: Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Inhibitor Chromosomal Location of Human Ortholog: 10p12.3-p11.2 Cellular Component: cytoplasm; integral to membrane; plasma membrane Molecular Function:frizzled binding; punt binding Biological Process: regulation of cell shape; cell migration; positive regulation of protein binding; positive regulation of transcription, DNA-dependent; transforming growth factor beta receptor signaling pathway; positive regulation of cell proliferation; negative regulation of transforming growth factor beta receptor signaling pathway |
NCBI Summary: | This gene encodes a transmembrane glycoprotein related to the type I receptors of the transforming growth factor-beta (TGF-beta) family, whose members play important roles in signal transduction in many developmental and pathological processes. The encoded protein however is a pseudoreceptor, lacking an intracellular serine/threonine kinase domain required for signaling. Similar proteins in frog, mouse and zebrafish function as negative regulators of TGF-beta, which has led to the suggestion that the encoded protein may function to limit the signaling range of the TGF-beta family during early embryogenesis. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q13145 |
NCBI GenInfo Identifier: | 2498645 |
NCBI Gene ID: | 25805 |
NCBI Accession: | Q13145.1 |
UniProt Related Accession: | Q13145 |
Molecular Weight: | 260 |
NCBI Full Name: | BMP and activin membrane-bound inhibitor homolog |
NCBI Synonym Full Names: | BMP and activin membrane-bound inhibitor |
NCBI Official Symbol: | BAMBI |
NCBI Official Synonym Symbols: | NMA |
NCBI Protein Information: | BMP and activin membrane-bound inhibitor homolog; non-metastatic gene A protein; putative transmembrane protein NMA |
UniProt Protein Name: | BMP and activin membrane-bound inhibitor homolog |
UniProt Synonym Protein Names: | Non-metastatic gene A protein; Putative transmembrane protein NMA |
Protein Family: | BMP and activin membrane-bound inhibitor |
UniProt Gene Name: | BAMBI |
UniProt Entry Name: | BAMBI_HUMAN |