BAG5 Antibody, HRP conjugated (PACO42339)
- SKU:
- PACO42339
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | BAG5 Antibody, HRP conjugated (PACO42339) |
抗体コード: | PACO42339 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human BAG family molecular chaperone regulator 5 protein (1-447AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | Inhibits both auto-ubiquitination of PARK2 and ubiquitination of target proteins by PARK2 By similarity. May function as a nucleotide exchange factor for HSP/HSP70, promoting ADP release, and activating Hsp70-mediated refolding. |
シノニム: | BAG family molecular chaperone regulator 5 (BAG-5) (Bcl-2-associated athanogene 5), BAG5, KIAA0873 |
UniProt Protein Function: | BAG5: Inhibits both auto-ubiquitination of PARK2 and ubiquitination of target proteins by PARK2. May function as a nucleotide exchange factor for HSP/HSP70, promoting ADP release, and activating Hsp70-mediated refolding. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Chromosomal Location of Human Ortholog: 14q32.33 Cellular Component: membrane; mitochondrion; perinuclear region of cytoplasm; inclusion body; nucleus Molecular Function:protein binding; chaperone binding; ubiquitin protein ligase binding; protein kinase binding Biological Process: protein folding; negative regulation of ubiquitin-protein ligase activity; negative regulation of protein ubiquitination; negative regulation of proteasomal ubiquitin-dependent protein catabolic process |
NCBI Summary: | The protein encoded by this gene is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9UL15 |
NCBI GenInfo Identifier: | 12643895 |
NCBI Gene ID: | 9529 |
NCBI Accession: | Q9UL15.1 |
UniProt Secondary Accession: | Q9UL15,O94950, Q86W59, |
UniProt Related Accession: | Q9UL15 |
Molecular Weight: | 447 |
NCBI Full Name: | BAG family molecular chaperone regulator 5 |
NCBI Synonym Full Names: | BCL2-associated athanogene 5 |
NCBI Official Symbol: | BAG5 |
NCBI Official Synonym Symbols: | BAG-5 |
NCBI Protein Information: | BAG family molecular chaperone regulator 5; bcl-2-associated athanogene 5; BAG-family molecular chaperone regulator-5 |
UniProt Protein Name: | BAG family molecular chaperone regulator 5 |
UniProt Synonym Protein Names: | Bcl-2-associated athanogene 5 |
Protein Family: | BAG family molecular chaperone regulator |
UniProt Gene Name: | BAG5 |
UniProt Entry Name: | BAG5_HUMAN |