B4GALT3 Antibody, FITC conjugated (PACO26287)
- SKU:
- PACO26287
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- FITC
Frequently bought together:
Description
抗体名: | B4GALT3 Antibody, FITC conjugated (PACO26287) |
抗体コード: | PACO26287 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Beta-1,4-galactosyltransferase 3 protein (34-393AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | FITC |
シノニム: | Beta-1,4-galactosyltransferase 3 (Beta-1,4-GalTase 3) (Beta4Gal-T3) (b4Gal-T3) (EC 2.4.1.-) (UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 3) (UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 3) [Includes: N-acetyllactosamine synthase (EC 2.4.1.90) (Nal synthase); Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase (EC 2.4.1.38); Beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase (EC 2.4.1.-)], B4GALT3 |
UniProt Protein Function: | B4GALT3: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids. Belongs to the glycosyltransferase 7 family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:EC 2.4.1.38; EC 2.4.1.90; Glycan Metabolism - N-glycan biosynthesis; Glycan Metabolism - glycosphingolipid biosynthesis - lacto and neolacto series; Glycan Metabolism - keratan sulfate biosynthesis; Membrane protein, integral; Transferase Chromosomal Location of Human Ortholog: 1q23.3 Cellular Component: cytosol; Golgi apparatus; Golgi membrane Molecular Function:beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity; galactosyltransferase activity Biological Process: keratan sulfate biosynthetic process |
NCBI Summary: | This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. This gene encodes an enzyme that may be mainly involved in the synthesis of the first N-acetyllactosamine unit of poly-N-acetyllactosamine chains. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Dec 2010] |
UniProt Code: | O60512 |
NCBI GenInfo Identifier: | 68053339 |
NCBI Gene ID: | 8703 |
NCBI Accession: | O60512.2 |
UniProt Secondary Accession: | O60512,O60910, Q9BPZ4, Q9H8T2, D3DVG3, |
UniProt Related Accession: | O60512 |
Molecular Weight: | 44kDa |
NCBI Full Name: | Beta-1,4-galactosyltransferase 3 |
NCBI Synonym Full Names: | beta-1,4-galactosyltransferase 3 |
NCBI Official Symbol: | B4GALT3 |
NCBI Official Synonym Symbols: | beta4Gal-T3 |
NCBI Protein Information: | beta-1,4-galactosyltransferase 3 |
UniProt Protein Name: | Beta-1,4-galactosyltransferase 3 |
UniProt Synonym Protein Names: | UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 3; UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 3Including the following 3 domains:N-acetyllactosamine synthase (EC:2.4.1.90)Alternative name(s):Nal synthase |
Protein Family: | Beta-1,4-galactosyltransferase |
UniProt Gene Name: | B4GALT3 |