ATRN Antibody (PACO19332)
- SKU:
- PACO19332
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | ATRN Antibody (PACO19332) |
抗体コード: | PACO19332 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:2000-1:5000, IHC:1:50-1:200 |
反応性: | Human, Mouse, Rat |
免疫原: | Synthetic peptide of human ATRN |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO19332(ATRN Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: x200). |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using PACO19332(ATRN Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: x200). |
バックグラウンド: | Multiple transcript variants encoding different isoforms exist for this gene. One of the isoforms is a membrane-bound protein with sequence similarity to the mouse mahogany protein, a receptor involved in controlling obesity. The other two isoforms are secreted proteins involved in the initial immune cell clustering during inflammatory responses that may regulate the chemotactic activity of chemokines. |
シノニム: | attractin |
UniProt Protein Function: | ATRN: Involved in the initial immune cell clustering during inflammatory response and may regulate chemotactic activity of chemokines. May play a role in melanocortin signaling pathways that regulate energy homeostasis and hair color. Low-affinity receptor for agouti. Has a critical role in normal myelination in the central nervous system. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Receptor, misc.; Membrane protein, integral Chromosomal Location of Human Ortholog: 20p13 Cellular Component: extracellular space; integral to plasma membrane |
NCBI Summary: | This gene encodes both membrane-bound and secreted protein isoforms. A membrane-bound isoform exhibits sequence similarity with the mouse mahogany protein, a receptor involved in controlling obesity. A secreted isoform is involved in the initial immune cell clustering during inflammatory responses that may regulate the chemotactic activity of chemokines. [provided by RefSeq, Apr 2016] |
UniProt Code: | O75882 |
NCBI GenInfo Identifier: | 13431311 |
NCBI Gene ID: | 8455 |
NCBI Accession: | O75882.2 |
UniProt Secondary Accession: | O75882,O60295, O95414, Q3MIT3, Q5TDA2, Q5TDA4, Q5VYW3 Q9NTQ3, Q9NTQ4, Q9NU01, Q9NZ57, A8KAE5, |
UniProt Related Accession: | O75882 |
Molecular Weight: | 133,702 Da |
NCBI Full Name: | Attractin |
NCBI Synonym Full Names: | attractin |
NCBI Official Symbol: | ATRN |
NCBI Official Synonym Symbols: | MGCA; DPPT-L |
NCBI Protein Information: | attractin |
UniProt Protein Name: | Attractin |
UniProt Synonym Protein Names: | DPPT-L; Mahogany homolog |
UniProt Gene Name: | ATRN |
UniProt Entry Name: | ATRN_HUMAN |
Antibodies |
Anti-ATRN Antibody (CAB10679) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
Recommended Products |
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |