ATP1B3 Antibody, FITC conjugated (PACO25130)
- SKU:
- PACO25130
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- FITC
Frequently bought together:
Description
抗体名: | ATP1B3 Antibody, FITC conjugated (PACO25130) |
抗体コード: | PACO25130 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Sodium/potassium-transporting ATPase subunit beta-3 protein (57-279AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | FITC |
バックグラウンド: | This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-3 subunit is not known. |
シノニム: | Sodium/potassium-transporting ATPase subunit beta-3 (Sodium/potassium-dependent ATPase subunit beta-3) (ATPB-3) (CD antigen CD298), ATP1B3 |
UniProt Protein Function: | ATP1B3: This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-3 subunit is not known. Belongs to the X(+)/potassium ATPases subunit beta family.Protein type: Membrane protein, integral; TransporterChromosomal Location of Human Ortholog: 3q23Cellular Component: plasma membrane; sodium:potassium-exchanging ATPase complexMolecular Function: ATPase activator activity; ATPase binding; sodium:potassium-exchanging ATPase activityBiological Process: cellular potassium ion homeostasis; cellular sodium ion homeostasis; leukocyte migration; positive regulation of ATPase activity; potassium ion import; protein stabilization; transport |
UniProt Protein Details: | |
NCBI Summary: | The protein encoded by this gene belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes a beta 3 subunit. This gene encodes a beta 3 subunit. A pseudogene exists for this gene, and it is located on chromosome 2. [provided by RefSeq, Jul 2008] |
UniProt Code: | P54709 |
NCBI GenInfo Identifier: | 1703470 |
NCBI Gene ID: | 483 |
NCBI Accession: | P54709.1 |
UniProt Secondary Accession: | P54709,B7Z1N7 |
UniProt Related Accession: | P54709 |
Molecular Weight: | 21,713 Da |
NCBI Full Name: | Sodium/potassium-transporting ATPase subunit beta-3 |
NCBI Synonym Full Names: | ATPase Na+/K+ transporting subunit beta 3 |
NCBI Official Symbol: | ATP1B3 |
NCBI Official Synonym Symbols: | CD298; ATPB-3 |
NCBI Protein Information: | sodium/potassium-transporting ATPase subunit beta-3 |
UniProt Protein Name: | Sodium/potassium-transporting ATPase subunit beta-3 |
UniProt Synonym Protein Names: | Sodium/potassium-dependent ATPase subunit beta-3; ATPB-3; CD_antigen: CD298 |
Protein Family: | |
UniProt Gene Name: | ATP1B3 |
UniProt Entry Name: | AT1B3_HUMAN |