ATF6B Antibody (PACO07899)
- SKU:
- PACO07899
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | ATF6B Antibody (PACO07899) |
抗体コード: | PACO07899 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC, IF |
推奨される希釈: | |
反応性: | Human, Mouse, Rat |
免疫原: | Human ATF6B |
憲法: | Liquid |
ストレージバッファ: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
精製方法: | Antigen Affinity purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | activating transcription factor 6 β;ATF6B;CREB-RP;CREBL1;FLJ10066;G13 ; |
UniProt Protein Function: | ATF6B: Transcriptional factor that acts in the unfolded protein response (UPR) pathway by activating UPR target genes induced during ER stress. Binds DNA on the 5'-CCAC[GA]-3' half of the ER stress response element (ERSE) (5'-CCAATN(9)CCAC[GA]-3') when NF-Y is bound to ERSE. Belongs to the bZIP family. ATF subfamily. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Transcription factor Chromosomal Location of Human Ortholog: 6p21.3 Cellular Component: endoplasmic reticulum membrane; Golgi apparatus; integral to endoplasmic reticulum membrane; intracellular; nucleus Molecular Function:protein binding; transcription factor activity Biological Process: signal transduction |
NCBI Summary: | The protein encoded by this gene is a transcription factor in the unfolded protein response (UPR) pathway during ER stress. Either as a homodimer or as a heterodimer with ATF6-alpha, the encoded protein binds to the ER stress response element, interacting with nuclear transcription factor Y to activate UPR target genes. The protein is normally found in the membrane of the endoplasmic reticulum; however, under ER stress, the N-terminal cytoplasmic domain is cleaved from the rest of the protein and translocates to the nucleus. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008] |
UniProt Code: | Q99941 |
NCBI GenInfo Identifier: | 20137431 |
NCBI Gene ID: | 1388 |
NCBI Accession: | Q99941.2 |
UniProt Secondary Accession: | Q99941,Q13269, Q14343, Q14345, Q5SSW7, Q99635, Q99637 Q9H3V9, Q9H3W1, Q9NPL0, B0UYX6, |
UniProt Related Accession: | Q99941 |
Molecular Weight: | 76,412 Da |
NCBI Full Name: | Cyclic AMP-dependent transcription factor ATF-6 beta |
NCBI Synonym Full Names: | activating transcription factor 6 beta |
NCBI Official Symbol: | ATF6B |
NCBI Official Synonym Symbols: | G13; CREBL1; CREB-RP |
NCBI Protein Information: | cyclic AMP-dependent transcription factor ATF-6 beta |
UniProt Protein Name: | Cyclic AMP-dependent transcription factor ATF-6 beta |
UniProt Synonym Protein Names: | Activating transcription factor 6 beta; ATF6-beta |
Protein Family: | Cyclic AMP-dependent transcription factor |
UniProt Gene Name: | ATF6B |
UniProt Entry Name: | ATF6B_HUMAN |