ASTN2 Antibody (PACO49406)
- SKU:
- PACO49406
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | ASTN2 Antibody (PACO49406) |
抗体コード: | PACO49406 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC, IF |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200 |
反応性: | Human |
免疫原: | Recombinant Human Astrotactin-2 protein (108-272AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Western Blot. Positive WB detected in: PC-3 whole cell lysate. All lanes: ASTN2 antibody at 3.4µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 149, 143, 148, 50, 45 kDa. Observed band size: 149 kDa.. | |
Immunohistochemistry of paraffin-embedded human colon cancer using PACO49406 at dilution of 1:100. | |
Immunohistochemistry of paraffin-embedded human thyroid tissue using PACO49406 at dilution of 1:100. |
バックグラウンド: | Mediates recycling of the neuronal cell adhesion molecule ASTN1 to the anterior pole of the cell membrane in migrating neurons. Promotes ASTN1 internalization and intracellular transport of endocytosed ASTN1 (By similarity). Selectively binds inositol-4,5-bisphosphate, inositol-3,4,5-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, suggesting it is recruited to membranes that contain lipids with a phosphoinositide headgroup (Ref.6). |
シノニム: | Astrotactin-2, ASTN2, KIAA0634 |
UniProt Protein Function: | ASTN2: a protein that is expressed in the brain and may function in neuronal migration, based on functional studies of the related astrotactin 1 gene in human and mouse. A deletion at this locus has been associated with schizophrenia. Multiple transcript variants encoding different proteins have been found for this locus. [provided by RefSeq, May 2010] |
UniProt Protein Details: | Protein type:Membrane protein, integral; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 9q33.1 Cellular Component: integral to membrane; endosome |
NCBI Summary: | This gene encodes a protein that is expressed in the brain and may function in neuronal migration, based on functional studies of the related astrotactin 1 gene in human and mouse. A deletion at this locus has been associated with schizophrenia. Multiple transcript variants encoding different proteins have been found for this locus. [provided by RefSeq, May 2010] |
UniProt Code: | O75129 |
NCBI GenInfo Identifier: | 296080736 |
NCBI Gene ID: | 23245 |
NCBI Accession: | NP_001171664.1 |
UniProt Secondary Accession: | O75129,Q52LQ2, Q5JVX8, Q5JVX9, Q5JVY1, Q5VXG8, Q5VZX6 Q8N6P8, Q8WV47, Q96FL4, A2A2T7, A2A2T9, |
UniProt Related Accession: | O75129 |
Molecular Weight: | |
NCBI Full Name: | astrotactin-2 isoform f |
NCBI Synonym Full Names: | astrotactin 2 |
NCBI Official Symbol: | ASTN2 |
NCBI Official Synonym Symbols: | bA67K19.1 |
NCBI Protein Information: | astrotactin-2 |
UniProt Protein Name: | Astrotactin-2 |
Protein Family: | Astrotactin |
UniProt Gene Name: | ASTN2 |
UniProt Entry Name: | ASTN2_HUMAN |
Antibodies |
Anti-ASTN2 Antibody (CAB18322) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
Anti-HRP-conjugated Beta Actin Antibody (CABC028) |