ASB4 Antibody, FITC conjugated (PACO51264)
- SKU:
- PACO51264
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- FITC
Frequently bought together:
Description
抗体名: | ASB4 Antibody, FITC conjugated (PACO51264) |
抗体コード: | PACO51264 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Ankyrin repeat and SOCS box protein 4 protein (166-321AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | FITC |
バックグラウンド: | Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Promotes differentiation and maturation of the vascular lineage by an oxygen-dependent mechanism (By similarity). |
シノニム: | Ankyrin repeat and SOCS box protein 4 (ASB-4), ASB4 |
UniProt Protein Function: | ASB4: Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Promotes differentiation and maturation of the vascular lineage by an oxygen-dependent mechanism. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Unknown function Chromosomal Location of Human Ortholog: 7q21-q22 Cellular Component: Cul2-RING ubiquitin ligase complex; Cul5-RING ubiquitin ligase complex |
NCBI Summary: | The protein encoded by this gene is a member of the ankyrin repeat and SOCS box-containing (ASB) family of proteins. They contain ankyrin repeat sequence and SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. Multiple alternatively spliced transcript variants have been described for this gene but some of the full length sequences are not known. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9Y574 |
NCBI GenInfo Identifier: | 20532003 |
NCBI Gene ID: | 51666 |
NCBI Accession: | Q9Y574.1 |
UniProt Secondary Accession: | Q9Y574,O14586, Q14D68, Q8TBT2, A4D1H6, |
UniProt Related Accession: | Q9Y574 |
Molecular Weight: | 38,931 Da |
NCBI Full Name: | Ankyrin repeat and SOCS box protein 4 |
NCBI Synonym Full Names: | ankyrin repeat and SOCS box containing 4 |
NCBI Official Symbol: | ASB4 |
NCBI Official Synonym Symbols: | ASB-4 |
NCBI Protein Information: | ankyrin repeat and SOCS box protein 4 |
UniProt Protein Name: | Ankyrin repeat and SOCS box protein 4 |
Protein Family: | Ankyrin repeat and SOCS box protein |
UniProt Gene Name: | ASB4 |
UniProt Entry Name: | ASB4_HUMAN |