ARRDC3 Antibody, Biotin conjugated (PACO38693)
- SKU:
- PACO38693
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- Biotin
Frequently bought together:
Description
抗体名: | ARRDC3 Antibody, Biotin conjugated (PACO38693) |
抗体コード: | PACO38693 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Arrestin domain-containing protein 3 protein (1-270AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Biotin |
バックグラウンド: | Adapter protein that plays a role in regulating cell-surface expression of adrenergic receptors and probably also other G protein-coupled receptors. Plays a role in NEDD4-mediated ubiquitination and endocytosis af activated ADRB2 and subsequent ADRB2 degradation. May recruit NEDD4 to ADRB2. Alternatively, may function as adapter protein that does not play a major role in recruiting NEDD4 to ADRB2, but rather plays a role in a targeting ADRB2 to endosomes. |
シノニム: | Arrestin domain-containing protein 3 (TBP-2-like inducible membrane protein) (TLIMP), ARRDC3, KIAA1376 |
UniProt Protein Function: | ARRDC3: Belongs to the arrestin family. |
UniProt Protein Details: | Protein type:Unknown function Chromosomal Location of Human Ortholog: 5q14.3 Cellular Component: endosome; plasma membrane Molecular Function:beta-3 adrenergic receptor binding; protein binding Biological Process: positive regulation of ubiquitin-protein ligase activity |
NCBI Summary: | This gene encodes a member of the arrestin family of proteins, which regulate G protein-mediated signaling. The encoded protein is thought to act as a regulator of breast cancer growth and progression by binding to a phosphorylated form of integrin beta4, a tumor-related antigen, targeting the integrin for internalization and degradation. [provided by RefSeq, Jul 2016] |
UniProt Code: | Q96B67 |
NCBI GenInfo Identifier: | 74731205 |
NCBI Gene ID: | 57561 |
NCBI Accession: | Q96B67.1 |
UniProt Secondary Accession: | Q96B67,Q9P2H1, A8K6T8, |
UniProt Related Accession: | Q96B67 |
Molecular Weight: | 46kDa |
NCBI Full Name: | Arrestin domain-containing protein 3 |
NCBI Synonym Full Names: | arrestin domain containing 3 |
NCBI Official Symbol: | ARRDC3 |
NCBI Official Synonym Symbols: | TLIMP |
NCBI Protein Information: | arrestin domain-containing protein 3 |
UniProt Protein Name: | Arrestin domain-containing protein 3 |
UniProt Synonym Protein Names: | TBP-2-like inducible membrane protein |
Protein Family: | Arrestin domain-containing protein |
UniProt Gene Name: | ARRDC3 |