ARPC2 Antibody (PACO18583)
- SKU:
- PACO18583
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | ARPC2 Antibody (PACO18583) |
抗体コード: | PACO18583 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100 |
反応性: | Human, Mouse, Rat |
免疫原: | Synthetic peptide of human ARPC2 |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using PACO18583(ARPC2 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200). |
![]() | Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-4: 231 cells, human fetal brain tissue, NIH/3T3 cells, PC3 cells, Primary antibody: PACO18583(ARPC2 Antibody) at dilution 1/350, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 40 seconds. |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO18583(ARPC2 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: x200). |
バックグラウンド: | This gene encodes one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution. The exact role of the protein encoded by this gene, the p34 subunit, has yet to be determined. Two alternatively spliced variants have been characterized to date. Additional alternatively spliced variants have been described but their full length nature has not been determined. |
シノニム: | actin related protein 2/3 complex, subunit 2, 34kDa |
UniProt Protein Function: | ARPC2: Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the mother actin filament. Belongs to the ARPC2 family. |
UniProt Protein Details: | Protein type:Actin-binding; Motility/polarity/chemotaxis; Cytoskeletal Chromosomal Location of Human Ortholog: 2q36.1 Cellular Component: Golgi apparatus; Arp2/3 protein complex; neuron projection; focal adhesion; cytoplasm; leading edge; plasma membrane; synapse; cytosol; endosome; actin cytoskeleton Molecular Function:actin filament binding; protein binding; structural constituent of cytoskeleton; kinesin binding Biological Process: axon guidance; ephrin receptor signaling pathway; innate immune response; cell motility |
NCBI Summary: | This gene encodes one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution. The exact role of the protein encoded by this gene, the p34 subunit, has yet to be determined. Two alternatively spliced variants have been characterized to date. Additional alternatively spliced variants have been described but their full length nature has not been determined. [provided by RefSeq, Jul 2008] |
UniProt Code: | O15144 |
NCBI GenInfo Identifier: | 3121764 |
NCBI Gene ID: | 10109 |
NCBI Accession: | O15144.1 |
UniProt Secondary Accession: | O15144,Q92801, Q9P1D4, |
UniProt Related Accession: | O15144 |
Molecular Weight: | 34,333 Da |
NCBI Full Name: | Actin-related protein 2/3 complex subunit 2 |
NCBI Synonym Full Names: | actin related protein 2/3 complex, subunit 2, 34kDa |
NCBI Official Symbol: | ARPC2 |
NCBI Official Synonym Symbols: | ARC34; PRO2446; p34-Arc; PNAS-139 |
NCBI Protein Information: | actin-related protein 2/3 complex subunit 2; ARP2/3 protein complex subunit 34; arp2/3 complex 34 kDa subunit |
UniProt Protein Name: | Actin-related protein 2/3 complex subunit 2 |
UniProt Synonym Protein Names: | Arp2/3 complex 34 kDa subunit; p34-ARC |
UniProt Gene Name: | ARPC2 |
UniProt Entry Name: | ARPC2_HUMAN |