ARPC1A Antibody (PACO53538)
- SKU:
- PACO53538
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | ARPC1A Antibody (PACO53538) |
抗体コード: | PACO53538 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IF |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IF:1:50-1:200 |
反応性: | Human |
免疫原: | Recombinant Human Actin-related protein 2/3 complex subunit 1A protein (175-317AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | Western Blot. Positive WB detected in: Hela whole cell lysate, HEK293 whole cell lysate. All lanes: ARPC1A antibody at 4µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 42, 39 kDa. Observed band size: 42 kDa. |
![]() | Immunofluorescent analysis of Hela cells using PACO53538 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
バックグラウンド: | Probably functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. |
シノニム: | Actin-related protein 2/3 complex subunit 1A (SOP2-like protein), ARPC1A, SOP2L |
UniProt Protein Function: | ARPC1A: Probably functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Belongs to the WD repeat ARPC1 family. |
UniProt Protein Details: | Protein type:Cytoskeletal; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 7q22.1 Cellular Component: Arp2/3 protein complex; cytosol; actin cytoskeleton Molecular Function:actin filament binding; actin binding Biological Process: axon guidance; ephrin receptor signaling pathway; innate immune response; actin cytoskeleton organization and biogenesis |
NCBI Summary: | This gene encodes one of seven subunits of the human Arp2/3 protein complex. This subunit is a member of the SOP2 family of proteins and is most similar to the protein encoded by gene ARPC1B. The similarity between these two proteins suggests that they both may function as p41 subunit of the human Arp2/3 complex that has been implicated in the control of actin polymerization in cells. It is possible that the p41 subunit is involved in assembling and maintaining the structure of the Arp2/3 complex. Multiple versions of the p41 subunit may adapt the functions of the complex to different cell types or developmental stages. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010] |
UniProt Code: | Q92747 |
NCBI GenInfo Identifier: | 88984001 |
NCBI Gene ID: | 10552 |
NCBI Accession: | Q92747.2 |
UniProt Related Accession: | Q92747 |
Molecular Weight: | 38kDa; 41kDa |
NCBI Full Name: | Actin-related protein 2/3 complex subunit 1A |
NCBI Synonym Full Names: | actin related protein 2/3 complex subunit 1A |
NCBI Official Symbol: | ARPC1A |
NCBI Official Synonym Symbols: | Arc40; SOP2L; HEL-68; SOP2Hs; HEL-S-307 |
NCBI Protein Information: | actin-related protein 2/3 complex subunit 1A |
UniProt Protein Name: | Actin-related protein 2/3 complex subunit 1A |
UniProt Synonym Protein Names: | SOP2-like protein |
Protein Family: | Actin-related protein 2/3 complex |
UniProt Gene Name: | ARPC1A |
UniProt Entry Name: | ARC1A_HUMAN |