ARL4C Antibody, FITC conjugated (PACO25046)
- SKU:
- PACO25046
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- FITC
Frequently bought together:
Description
抗体名: | ARL4C Antibody, FITC conjugated (PACO25046) |
抗体コード: | PACO25046 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human ADP-ribosylation factor-like protein 4C protein (2-192AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | FITC |
バックグラウンド: | Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. May be involved in transport between a perinuclear compartment and the plasma membrane, apparently linked to the ABCA1-mediated cholesterol secretion pathway. Recruits CYTH1, CYTH2, CYTH3 and CYTH4 to the plasma membrane in the GDP-bound form. Regulates the microtubule-dependent intracellular vesicular transport from early endosome to recycling endosome process. |
シノニム: | ADP-ribosylation factor-like protein 4C (ADP-ribosylation factor-like protein 7) (ADP-ribosylation factor-like protein LAK), ARL4C, ARL7 |
UniProt Protein Function: | ARL4C: Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. May be involved in transport between a perinuclear compartment and the plasma membrane, apparently linked to the ABCA1-mediated cholesterol secretion pathway. Recruits CYTH1, CYTH2, CYTH3 and CYTH4 to the plasma membrane in the GDP- bound form. Regulates the microtubule-dependent intracellular vesicular transport from early endosome to recycling endosome process. Belongs to the small GTPase superfamily. Arf family. |
UniProt Protein Details: | Protein type:G protein; G protein, monomeric, ARF; G protein, monomeric Chromosomal Location of Human Ortholog: 2q37.1 Cellular Component: cytoplasm; plasma membrane; nucleus; filopodium Molecular Function:GTPase activity; protein binding; GTP binding; alpha-tubulin binding Biological Process: metabolic process; small GTPase mediated signal transduction; endocytic recycling |
NCBI Summary: | ADP-ribosylation factor-like 4C is a member of the ADP-ribosylation factor family of GTP-binding proteins. ARL4C is closely similar to ARL4A and ARL4D and each has a nuclear localization signal and an unusually high guanine nucleotide exchange rate. This protein may play a role in cholesterol transport. [provided by RefSeq, Jul 2008] |
UniProt Code: | P56559 |
NCBI GenInfo Identifier: | 540344578 |
NCBI Gene ID: | 10123 |
NCBI Accession: | NP_001269360.1 |
UniProt Secondary Accession: | P56559,Q4A519, Q53R10, Q9BVN1, Q9UQ34, |
UniProt Related Accession: | P56559 |
Molecular Weight: | 22,448 Da |
NCBI Full Name: | ADP-ribosylation factor-like protein 4C isoform 1 |
NCBI Synonym Full Names: | ADP-ribosylation factor-like 4C |
NCBI Official Symbol: | ARL4C |
NCBI Official Synonym Symbols: | LAK; ARL7 |
NCBI Protein Information: | ADP-ribosylation factor-like protein 4C; ADP-ribosylation factor-like 7; ADP ribosylation factor-like protein 7; ADP-ribosylation factor-like protein 7; ADP-ribosylation factor-like protein LAK |
UniProt Protein Name: | ADP-ribosylation factor-like protein 4C |
UniProt Synonym Protein Names: | ADP-ribosylation factor-like protein 7; ADP-ribosylation factor-like protein LAK |
Protein Family: | ADP-ribosylation factor-like protein |
UniProt Gene Name: | ARL4C |
UniProt Entry Name: | ARL4C_HUMAN |