ARL2BP Antibody, HRP conjugated (PACO63536)
- SKU:
- PACO63536
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | ARL2BP Antibody, HRP conjugated (PACO63536) |
抗体コード: | PACO63536 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human ADP-ribosylation factor-like protein 2-binding protein (1-163AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | Antigen Affinity Purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. May play a role as an effector of ARL2. |
シノニム: | ADP-ribosylation factor-like protein 2-binding protein (ARF-like 2-binding protein) (ARL2-binding protein) (Binder of ARF2 protein 1), ARL2BP, BART BART1 |
UniProt Protein Function: | ARL2BP: Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. May play a role as an effector of ARL2. Belongs to the ARL2BP family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:G protein regulator, misc.; Mitochondrial Chromosomal Location of Human Ortholog: 16q13 Cellular Component: centrosome; cytosol; midbody; mitochondrial intermembrane space; mitochondrial matrix Molecular Function:GTPase regulator activity; protein binding; transcription coactivator activity Biological Process: maintenance of protein localization in nucleus; positive regulation of tyrosine phosphorylation of STAT protein; regulation of insulin secretion; signal transduction Disease: Retinitis Pigmentosa With Or Without Situs Inversus |
NCBI Summary: | ADP-ribosylation factor (ARF)-like proteins (ARLs) comprise a functionally distinct group of the ARF family of RAS-related GTPases. The protein encoded by this gene binds to ARL2.GTP with high affinity but does not interact with ARL2.GDP, activated ARF, or RHO proteins. The lack of detectable membrane association of this protein or ARL2 upon activation of ARL2 is suggestive of actions distinct from those of the ARFs. This protein is considered to be the first ARL2-specific effector identified, due to its interaction with ARL2.GTP but lack of ARL2 GTPase-activating protein activity. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9Y2Y0 |
NCBI GenInfo Identifier: | 6912268 |
NCBI Gene ID: | 23568 |
NCBI Accession: | NP_036238.1 |
UniProt Secondary Accession: | Q9Y2Y0,Q504R0, B3KQJ5, |
UniProt Related Accession: | Q9Y2Y0 |
Molecular Weight: | 46.2kD |
NCBI Full Name: | ADP-ribosylation factor-like protein 2-binding protein |
NCBI Synonym Full Names: | ADP ribosylation factor like GTPase 2 binding protein |
NCBI Official Symbol: | ARL2BP |
NCBI Official Synonym Symbols: | BART; RP66; BART1 |
NCBI Protein Information: | ADP-ribosylation factor-like protein 2-binding protein |
UniProt Protein Name: | ADP-ribosylation factor-like protein 2-binding protein |
UniProt Synonym Protein Names: | Binder of ARF2 protein 1 |
Protein Family: | ADP-ribosylation factor-like protein |
UniProt Gene Name: | ARL2BP |