ARL1 Antibody, Biotin conjugated (PACO56727)
- SKU:
- PACO56727
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- Biotin
Frequently bought together:
Description
抗体名: | ARL1 Antibody, Biotin conjugated (PACO56727) |
抗体コード: | PACO56727 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human ADP-ribosylation factor-like protein 1 protein (2-181AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Biotin |
バックグラウンド: | GTP-binding protein that has very low efficiency as allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Can activate phospholipase D with very low efficiency. Important for normal function of the Golgi apparatus. |
シノニム: | ADP-ribosylation factor-like protein 1, ARL1 |
UniProt Protein Function: | ARL1: GTP-binding protein that has very low efficiency as allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Can activate phospholipase D with very low efficiency. Important for normal function of the Golgi apparatus. Belongs to the small GTPase superfamily. Arf family. |
UniProt Protein Details: | Protein type:G protein; G protein, monomeric; G protein, monomeric, ARF Chromosomal Location of Human Ortholog: 12q23.2 Cellular Component: Golgi membrane; Golgi apparatus; cytoplasm; trans-Golgi network Molecular Function:GTPase activity; protein domain specific binding; GTP binding; metal ion binding; enzyme activator activity Biological Process: phospholipase D activation; toxin metabolic process; protein localization in Golgi apparatus; small GTPase mediated signal transduction; retrograde transport, endosome to Golgi; Golgi organization and biogenesis; Golgi vesicle transport |
NCBI Summary: | The protein encoded by this gene belongs to the ARL (ADP-ribosylation factor-like) family of proteins, which are structurally related to ADP-ribosylation factors (ARFs). ARFs, described as activators of cholera toxin (CT) ADP-ribosyltransferase activity, regulate intracellular vesicular membrane trafficking, and stimulate a phospholipase D (PLD) isoform. Although, ARL proteins were initially thought not to activate CT or PLD, later work showed that they are weak stimulators of PLD and CT in a phospholipid dependent manner. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014] |
UniProt Code: | P40616 |
NCBI GenInfo Identifier: | 728888 |
NCBI Gene ID: | 400 |
NCBI Accession: | P40616.1 |
UniProt Related Accession: | P40616 |
Molecular Weight: | 20kDa |
NCBI Full Name: | ADP-ribosylation factor-like protein 1 |
NCBI Synonym Full Names: | ADP ribosylation factor like GTPase 1 |
NCBI Official Symbol: | ARL1 |
NCBI Official Synonym Symbols: | ARFL1 |
NCBI Protein Information: | ADP-ribosylation factor-like protein 1 |
UniProt Protein Name: | ADP-ribosylation factor-like protein 1 |
Protein Family: | ARL14 effector protein |
UniProt Gene Name: | ARL1 |
UniProt Entry Name: | ARL1_HUMAN |