AQP10 Antibody (PACO57400)
- SKU:
- PACO57400
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | AQP10 Antibody (PACO57400) |
抗体コード: | PACO57400 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, IHC, IF |
推奨される希釈: | ELISA:1:2000-1:10000, IHC:1:200-1:500, IF:1:50-1:200 |
反応性: | Human |
免疫原: | Recombinant Human Aquaporin-10 protein (209-301AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | Immunofluorescence staining of A549 cells with PACO57400 at 1:66, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
![]() | IHC image of PACO57400 diluted at 1:200 and staining in paraffin-embedded human small intestine tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
バックグラウンド: | Water channel required to promote glycerol permeability and water transport across cell membranes. May contribute to water transport in the upper portion of small intestine. Isoform 2 is not permeable to urea and glycerol. |
シノニム: | Aquaporin-10 (AQP-10) (Aquaglyceroporin-10) (Small intestine aquaporin), AQP10 |
UniProt Protein Function: | AQP10: Water channel required to promote glycerol permeability and water transport across cell membranes. May contribute to water transport in the upper portion of small intestine. Isoform 2 is not permeable to urea and glycerol. Belongs to the MIP/aquaporin (TC 1.A.8) family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Transporter, aquaporin family; Transporter; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 1q21.3 Cellular Component: integral to plasma membrane; plasma membrane Molecular Function:urea transmembrane transporter activity; water channel activity; glycerol channel activity Biological Process: glycerol transport; cellular water homeostasis; response to toxin; water transport; transmembrane transport |
NCBI Summary: | This gene encodes a member of the aquaglyceroporin family of integral membrane proteins. Members of this family function as water-permeable channels in the epithelia of organs that absorb and excrete water. This protein was shown to function as a water-selective channel, and could also permeate neutral solutes such as glycerol and urea. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q96PS8 |
NCBI GenInfo Identifier: | 47117905 |
NCBI Gene ID: | 89872 |
NCBI Accession: | Q96PS8.2 |
UniProt Secondary Accession: | Q96PS8,Q5VYD3, Q5VYD4, Q8NG70, |
UniProt Related Accession: | Q96PS8 |
Molecular Weight: | 301 |
NCBI Full Name: | Aquaporin-10 |
NCBI Synonym Full Names: | aquaporin 10 |
NCBI Official Symbol: | AQP10 |
NCBI Official Synonym Symbols: | AQPA_HUMAN |
NCBI Protein Information: | aquaporin-10; AQP-10; aquaglyceroporin-10; small intestine aquaporin |
UniProt Protein Name: | Aquaporin-10 |
UniProt Synonym Protein Names: | Aquaglyceroporin-10; Small intestine aquaporin |
Protein Family: | Aquaporin |
UniProt Gene Name: | AQP10 |
UniProt Entry Name: | AQP10_HUMAN |
Antibodies |
Anti-AQP10 Antibody (CAB2888) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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