APOH Antibody (PACO54426)
- SKU:
- PACO54426
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Description
抗体名: | APOH Antibody (PACO54426) |
抗体コード: | PACO54426 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC, IF |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200 |
反応性: | Human, Rat |
免疫原: | Recombinant Human Beta-2-glycoprotein 1 protein (119-345AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | Western Blot. Positive WB detected in: Rat liver tissue. All lanes: APOH antibody at 3.2µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 39 kDa. Observed band size: 39 kDa. |
![]() | Immunofluorescent analysis of HepG2 cells using PACO54426 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
![]() | Immunohistochemistry of paraffin-embedded human liver cancer using PACO54426 at dilution of 1:100. |
バックグラウンド: | Binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. May prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells. |
シノニム: | Beta-2-glycoprotein 1 (APC inhibitor) (Activated protein C-binding protein) (Anticardiolipin cofactor) (Apolipoprotein H) (Apo-H) (Beta-2-glycoprotein I) (B2GPI) (Beta(2)GPI), APOH, B2G1 |
UniProt Protein Function: | APOH: Binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. May prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells. |
UniProt Protein Details: | Protein type:Secreted; Lipid-binding; Secreted, signal peptide Chromosomal Location of Human Ortholog: 17q24.2 Cellular Component: extracellular matrix; extracellular space; chylomicron; cell surface Molecular Function:heparin binding; identical protein binding; protein binding; phospholipid binding; glycoprotein binding; lipid binding Biological Process: negative regulation of angiogenesis; negative regulation of myeloid cell apoptosis; triacylglycerol metabolic process; positive regulation of blood coagulation; negative regulation of fibrinolysis; negative regulation of endothelial cell proliferation; positive regulation of lipoprotein lipase activity; negative regulation of blood coagulation; triacylglycerol transport; blood coagulation, intrinsic pathway; plasminogen activation; regulation of fibrinolysis |
NCBI Summary: | Apolipoprotein H has been implicated in a variety of physiologic pathways including lipoprotein metabolism, coagulation, and the production of antiphospholipid autoantibodies. APOH may be a required cofactor for anionic phospholipid binding by the antiphospholipid autoantibodies found in sera of many patients with lupus and primary antiphospholipid syndrome, but it does not seem to be required for the reactivity of antiphospholipid autoantibodies associated with infections. [provided by RefSeq, Jul 2008] |
UniProt Code: | P02749 |
NCBI GenInfo Identifier: | 543826 |
NCBI Gene ID: | 350 |
NCBI Accession: | P02749.3 |
UniProt Secondary Accession: | P02749,Q9UCN7, B2R9M3, |
UniProt Related Accession: | P02749 |
Molecular Weight: | 345 |
NCBI Full Name: | Beta-2-glycoprotein 1 |
NCBI Synonym Full Names: | apolipoprotein H (beta-2-glycoprotein I) |
NCBI Official Symbol: | APOH |
NCBI Official Synonym Symbols: | BG; B2G1; B2GP1 |
NCBI Protein Information: | beta-2-glycoprotein 1; B2GPI; apo-H; beta(2)GPI; APC inhibitor; anticardiolipin cofactor; activated protein C-binding protein |
UniProt Protein Name: | Beta-2-glycoprotein 1 |
UniProt Synonym Protein Names: | APC inhibitor; Activated protein C-binding protein; Anticardiolipin cofactor; Apolipoprotein H; Apo-H; Beta-2-glycoprotein I; B2GPI; Beta(2)GPI |
Protein Family: | Beta-2-glycoprotein |
UniProt Gene Name: | APOH |
UniProt Entry Name: | APOH_HUMAN |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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