APBB2 Antibody (PACO04064)
- SKU:
- PACO04064
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | APBB2 Antibody |
抗体コード: | PACO04064 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | WB:1:500-1:2000, IHC:1:100-1:300 |
反応性: | Human, Mouse |
免疫原: | synthesized peptide derived from the Internal region of human Fe65L. |
憲法: | Liquid |
ストレージバッファ: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | APBB2; FE65L; FE65L1; Amyloid beta A4 precursor protein-binding family B member 2; Protein Fe65-like 1 |
UniProt Protein Function: | APBB2: May modulate the internalization of beta-amyloid precursor protein. 3 isoforms of the human protein are produced by alternative splicing.Protein type: ApoptosisChromosomal Location of Human Ortholog: 4p13Cellular Component: cytoplasm; growth cone; lamellipodium; membrane; nucleus; synapseMolecular Function: beta-amyloid binding; protein binding; transcription factor bindingBiological Process: axon guidance; cell cycle arrest; extracellular matrix organization and biogenesis; negative regulation of apoptosis; negative regulation of cell growth; neuron migration; positive regulation of apoptosis; regulation of transcription, DNA-dependentDisease: Alzheimer Disease |
UniProt Protein Details: | |
NCBI Summary: | The protein encoded by this gene interacts with the cytoplasmic domains of amyloid beta (A4) precursor protein and amyloid beta (A4) precursor-like protein 2. This protein contains two phosphotyrosine binding (PTB) domains, which are thought to function in signal transduction. Polymorphisms in this gene have been associated with Alzheimer's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009] |
UniProt Code: | Q92870 |
NCBI GenInfo Identifier: | 317373476 |
NCBI Gene ID: | 323 |
NCBI Accession: | Q92870.3 |
UniProt Secondary Accession: | Q92870,Q8IUI6, B4DSL4, E9PG87 |
UniProt Related Accession: | Q92870 |
Molecular Weight: | 83,445 Da |
NCBI Full Name: | Amyloid beta A4 protein-binding family B member 2 |
NCBI Synonym Full Names: | amyloid beta precursor protein binding family B member 2 |
NCBI Official Symbol: | APBB2 |
NCBI Official Synonym Symbols: | FE65L; FE65L1 |
NCBI Protein Information: | amyloid beta A4 precursor protein-binding family B member 2 |
UniProt Protein Name: | Amyloid beta A4 precursor protein-binding family B member 2 |
UniProt Synonym Protein Names: | Protein Fe65-like 1 |
Protein Family: | Amyloid beta A4 precursor protein-binding family |
UniProt Gene Name: | APBB2 |
UniProt Entry Name: | APBB2_HUMAN |