Anti-ZNF148 Antibody (CAB7001)
- SKU:
- CAB7001
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
抗体名: | Anti-ZNF148 Antibody |
抗体コード: | CAB7001 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC IF |
反応性: | Human, Mouse, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 690-794 of human ZNF148 (NP_068799.2). |
申し込み: | WB IHC IF |
推奨希釈: | WB 1:500 - 1:1000 IHC 1:50 - 1:100 IF 1:20 - 1:100 |
反応性: | Human, Mouse, Rat |
ポジティブサンプル: | K-562, Mouse lung, Rat lung |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 690-794 of human ZNF148 (NP_068799.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | SGDE TNHA SATS TQDF LDQV TSQK KAEA QPVH QAYQ MSSF EQPF RAPY HGSR AGIA TQFS TANG QVNL RGPG TSAE FSEF PLVN VNDN RAGM TSSP DATT GQTF G |
遺伝子ID: | 7707 |
Uniprot: | Q9UQR1 |
セルラーロケーション: | Nucleus |
計算された分子量: | 14kDa/88kDa |
観察された分子量: | 105kDa |
同義語: | ZNF148, BERF-1, BFCOL1, GDACCF, HT-BETA, ZBP-89, ZFP148, pHZ-52 |
バックグラウンド: | The protein encoded by this gene is a member of the Kruppel family of zinc finger DNA binding proteins. The encoded protein activates transcription of the T-cell receptor and intestinal alkaline phosphatase genes but represses transcription of the ornithine decarboxylase, vimentin, gastrin, stomelysin, and enolase genes. Increased expression of this gene results in decreased patient survival rates from colorectal cancer, while mutations in this gene have been associated with global developmental delay, hypoplastic corpus callosum, and dysmorphic facies. |
UniProt Protein Function: | ZNF148: a transcription factor. Represses the transcription of a number of genes including gastrin, stromelysin and enolase. Binds to the G-rich box in the enhancer region of these genes. Belongs to the krueppel C2H2-type zinc-finger protein family. |
UniProt Protein Details: | Protein type:C2H2-type zinc finger protein; DNA-binding; Transcription, coactivator/corepressor Chromosomal Location of Human Ortholog: 3q21 Cellular Component: Golgi apparatus; nucleoplasm Molecular Function:protein binding; sequence-specific DNA binding Biological Process: cellular defense response; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; substantia nigra development; transcription from RNA polymerase II promoter |
UniProt Code: | Q9UQR1 |
NCBI GenInfo Identifier: | 12643385 |
NCBI Gene ID: | 7707 |
NCBI Accession: | Q9UQR1.2 |
UniProt Secondary Accession: | Q9UQR1,O00389, O43591, Q58EY5, Q6PJ98, D3DN27, |
UniProt Related Accession: | Q9UQR1 |
Molecular Weight: | 14,473 Da |
NCBI Full Name: | Zinc finger protein 148 |
NCBI Synonym Full Names: | zinc finger protein 148 |
NCBI Official Symbol: | ZNF148 |
NCBI Official Synonym Symbols: | BERF-1; BFCOL1; ZBP-89; ZFP148; pHZ-52; HT-BETA |
NCBI Protein Information: | zinc finger protein 148 |
UniProt Protein Name: | Zinc finger protein 148 |
UniProt Synonym Protein Names: | Transcription factor ZBP-89; Zinc finger DNA-binding protein 89 |
Protein Family: | Zinc finger protein |
UniProt Gene Name: | ZNF148 |
UniProt Entry Name: | ZN148_HUMAN |
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