Anti-ZMYND8 Antibody (CAB8737)[KO Validated]
![Anti-ZMYND8 Antibody (CAB8737)[KO Validated]](https://cdn11.bigcommerce.com/s-d5atsu6k01/images/stencil/608x608/products/18445/18311/anti-zmynd8-antibody-cab8737ko-validated__01439__11766.1645803965.jpg?c=1 "Anti-ZMYND8 Antibody (CAB8737)[KO Validated]")
- SKU:
- CAB8737
- Product type:
- Antibody
- Application:
- WB
- Application:
- IHC
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Epigenetics and Nuclear Signaling
![Anti-ZMYND8 Antibody (CAB8737)[KO Validated]](https://cdn11.bigcommerce.com/s-d5atsu6k01/images/stencil/1280x1280/products/18445/18311/anti-zmynd8-antibody-cab8737ko-validated__01439__11766.1645803965.jpg?c=1&imbypass=on "Anti-ZMYND8 Antibody (CAB8737)[KO Validated]")
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Description
| 抗体名: | Anti-ZMYND8 Antibody [KO Validated] |
| 抗体コード: | CAB8737 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 959-1188 of human ZMYND8 (NP_898868.1). |
| 申し込み: | WB IHC |
| 推奨希釈: | WB 1:1000 - 1:2000 IHC 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | U-87 MG, LO2, MCF-7, A375 |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 959-1188 of human ZMYND8 (NP_898868.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | LELT MAEM RQSL EQER DRLI AEVK KQLE LEKQ QAVD ETKK KQWC ANCK KEAI FYCC WNTS YCDY PCQQ AHWP EHMK SCTQ SATA PQQE ADAE VNTE TLNK SSQG SSSS TQSA PSET ASAS KEKE TSAE KSKE SGST LDLS GSRE TPSS ILLG SNQG SVSK RCDK QPAY APTT TDHQ PHPN YPAQ KYHS RSNK SSWS SSDE KRGS TRSD HNTS TSTK SLLP KESR LDTF WD |
| 遺伝子ID: | 23613 |
| Uniprot: | Q9ULU4 |
| セルラーロケーション: | |
| 計算された分子量: | 66kDa/82kDa/109-138kDa |
| 観察された分子量: | 165kDa |
| 同義語: | ZMYND8, PRKCBP1, PRO2893, RACK7 |
| バックグラウンド: | The protein encoded by this gene is a receptor for activated C-kinase (RACK) protein. The encoded protein has been shown to bind in vitro to activated protein kinase C beta I. In addition, this protein is a cutaneous T-cell lymphoma-associated antigen. Finally, the protein contains a bromodomain and two zinc fingers, and is thought to be a transcriptional regulator. Multiple transcript variants encoding several different isoforms have been found for this gene. |
| UniProt Protein Function: | May act as a transcriptional corepressor for KDM5D. Required for KDM5D-mediated down-regulation of diverse metastasis-associated genes; the function seems to involve the recognition of the dual histone signature H3K4me1-H3K14ac. Suppresses prostate cancer cell invasion. |
| NCBI Summary: | The protein encoded by this gene is a receptor for activated C-kinase (RACK) protein. The encoded protein has been shown to bind in vitro to activated protein kinase C beta I. In addition, this protein is a cutaneous T-cell lymphoma-associated antigen. Finally, the protein contains a bromodomain and two zinc fingers, and is thought to be a transcriptional regulator. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9ULU4 |
| NCBI GenInfo Identifier: | 528881103 |
| NCBI Gene ID: | 23613 |
| NCBI Accession: | NP_001268700.1 |
| UniProt Secondary Accession: | Q9ULU4,Q13517, Q2HXV1, B3KVL2, B7Z2A8, B7Z3E0, B7Z680 B7ZM62, E1P5U5, F5H0X3, H7C0U2, J3KPU3, |
| UniProt Related Accession: | Q9ULU4 |
| Molecular Weight: | 131 kDa |
| NCBI Full Name: | protein kinase C-binding protein 1 isoform e |
| NCBI Synonym Full Names: | zinc finger MYND-type containing 8 |
| NCBI Official Symbol: | ZMYND8 |
| NCBI Official Synonym Symbols: | RACK7; PRKCBP1; PRO2893 |
| NCBI Protein Information: | protein kinase C-binding protein 1 |
| UniProt Protein Name: | Protein kinase C-binding protein 1 |
| UniProt Synonym Protein Names: | Cutaneous T-cell lymphoma-associated antigen se14-3; CTCL-associated antigen se14-3; Rack7; Zinc finger MYND domain-containing protein 8 |
| UniProt Gene Name: | ZMYND8 |
![Anti-ZMYND8 Polyclonal Antibody [KO Validated] (CAB8737)](https://cdn11.bigcommerce.com/s-h68l9z2lnx/product_images/x/063/A8737_1__94756.jpg) | Western blot analysis of extracts of various cell lines, using ZMYND8 antibody (CAB8737) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s. |
![Anti-ZMYND8 Polyclonal Antibody [KO Validated] (CAB8737)](https://cdn11.bigcommerce.com/s-h68l9z2lnx/product_images/t/130/A8737_2__29110.jpg) | Western blot analysis of extracts from normal (control) and ZMYND8 knockout (KO) HeLa cells, using ZMYND8 antibody (CAB8737) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s. |
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