Anti-ZMYM3 Antibody (CAB12990)
- SKU:
- CAB12990
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
| 抗体名: | Anti-ZMYM3 Antibody |
| 抗体コード: | CAB12990 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IHC |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 140-300 of human ZMYM3 (NP_001164634.1). |
| 申し込み: | WB IHC |
| 推奨希釈: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| 反応性: | Human |
| ポジティブサンプル: | HeLa |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 140-300 of human ZMYM3 (NP_001164634.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | LLEP LAPD SPIT LQSP HIEE EETT SIAT ARRG SPGQ EEEL PQGQ PQSP NAPP SPSV GETL GDGI NSSQ TKPG GSSP PAHP SLPG DGLT AKAS EKPP ERKR SERV RRAE PPKP EVVD STES IPVS DEDS DAMV DDPN DEDF VPFR PRRS PRMS LRSS VSQR A |
| 遺伝子ID: | 9203 |
| Uniprot: | Q14202 |
| セルラーロケーション: | Nucleus |
| 計算された分子量: | 52kDa/151kDa/152kDa |
| 観察された分子量: | 152kDa |
| 同義語: | ZMYM3, DXS6673E, MYM, XFIM, ZNF198L2, ZNF261 |
| バックグラウンド: | This gene is located on the X chromosome and is subject to X inactivation. It is highly conserved in vertebrates and most abundantly expressed in the brain. The encoded protein is a component of histone deacetylase-containing multiprotein complexes that function through modifying chromatin structure to keep genes silent. A chromosomal translocation (X;13) involving this gene is associated with X-linked mental retardation. Several alternatively spliced transcript variants have been found for this gene. |
| UniProt Protein Function: | ZNF261: Plays a role in the regulation of cell morphology and cytoskeletal organization. A chromosomal aberration involving ZMYM3 may be a cause of X-linked mental retardation in Xq13.1. Translocation t(X;13)(q13.1;?). 3 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:DNA-binding Chromosomal Location of Human Ortholog: Xq13.1 Cellular Component: nucleus Molecular Function:DNA binding; zinc ion binding Biological Process: multicellular organismal development; regulation of cell morphogenesis; cytoskeleton organization and biogenesis |
| UniProt Code: | Q14202 |
| NCBI GenInfo Identifier: | 283837896 |
| NCBI Gene ID: | 9203 |
| NCBI Accession: | NP_001164634.1 |
| UniProt Secondary Accession: | Q14202,O15089, Q96E26, D3DVV3, |
| UniProt Related Accession: | Q14202 |
| Molecular Weight: | 152,379 Da |
| NCBI Full Name: | zinc finger MYM-type protein 3 isoform 3 |
| NCBI Synonym Full Names: | zinc finger, MYM-type 3 |
| NCBI Official Symbol: | ZMYM3 |
| NCBI Official Synonym Symbols: | MYM; XFIM; ZNF261; DXS6673E; ZNF198L2 |
| NCBI Protein Information: | zinc finger MYM-type protein 3; zinc finger protein 261 |
| UniProt Protein Name: | Zinc finger MYM-type protein 3 |
| UniProt Synonym Protein Names: | Zinc finger protein 261 |
| Protein Family: | Zinc finger MYM-type protein |
| UniProt Gene Name: | ZMYM3 |
| UniProt Entry Name: | ZMYM3_HUMAN |
 | Western blot analysis of extracts of HeLa cells, using ZMYM3 antibody (CAB12990) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s. |
 | Immunohistochemistry of paraffin-embedded human tonsil using ZMYM3 antibody (CAB12990) at dilution of 1:100 (40x lens). |
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