Anti-ZFPM1 Antibody (CAB18183)
- SKU:
- CAB18183
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
Frequently bought together:
Description
| 抗体名: | Anti-ZFPM1 Antibody |
| 抗体コード: | CAB18183 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IF |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant protein of human ZFPM1 . |
| 申し込み: | WB IF |
| 推奨希釈: | WB 1:500 - 1:2000 IF 1:50 - 1:200 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | HepG2, Mouse liver, Mouse brain, Rat liver |
| 免疫原: | Recombinant protein of human ZFPM1 . |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | Email for sequence |
| 遺伝子ID: | 161882 |
| Uniprot: | Q8IX07 |
| セルラーロケーション: | |
| 計算された分子量: | 104kDa |
| 観察された分子量: | 104kDa |
 | Western blot - ZFPM1 Rabbit pAb (CAB18183) |
| 同義語: | FOG, FOG1, ZNF408, ZNF89A, ZC2HC11A, ZFPM1 |
| バックグラウンド: |
| UniProt Protein Function: | FOG1: Transcription regulator that plays an essential role in erythroid and megakaryocytic cell differentiation. Essential cofactor that acts via the formation of a heterodimer with transcription factors of the GATA family GATA1, GATA2 and GATA3. Such heterodimer can both activate or repress transcriptional activity, depending on the cell and promoter context. The heterodimer formed with GATA proteins is essential to activate expression of genes such as NFE2, ITGA2B, alpha- and beta-globin, while it represses expression of KLF1. May be involved in regulation of some genes in gonads. May also be involved in cardiac development, in a non-redundant way with ZFPM2/FOG2. Belongs to the FOG (Friend of GATA) family. |
| UniProt Protein Details: | Protein type:Transcription regulation; C2H2-type zinc finger protein Chromosomal Location of Human Ortholog: 16q24.2 Cellular Component: nucleoplasm; nucleus; transcription factor complex; transcriptional repressor complex Molecular Function:protein binding; transcription factor binding Biological Process: blood coagulation; cardiac muscle morphogensis; embryonic hemopoiesis; erythrocyte differentiation; heart development; megakaryocyte differentiation; negative regulation of fat cell differentiation; negative regulation of interleukin-4 biosynthetic process; negative regulation of protein binding; platelet formation; positive regulation of interferon-gamma biosynthetic process; T-helper cell lineage commitment |
| UniProt Code: | Q8IX07 |
| NCBI GenInfo Identifier: | 296434508 |
| NCBI Gene ID: | 161882 |
| NCBI Accession: | Q8IX07.2 |
| UniProt Related Accession: | Q8IX07 |
| Molecular Weight: | 104,888 Da |
| NCBI Full Name: | Zinc finger protein ZFPM1 |
| NCBI Synonym Full Names: | zinc finger protein, FOG family member 1 |
| NCBI Official Symbol: | ZFPM1 |
| NCBI Official Synonym Symbols: | FOG; FOG1; ZNF408; ZNF89A; ZC2HC11A |
| NCBI Protein Information: | zinc finger protein ZFPM1 |
| UniProt Protein Name: | Zinc finger protein ZFPM1 |
| UniProt Synonym Protein Names: | Friend of GATA protein 1; FOG-1; Friend of GATA 1; Zinc finger protein 89A; Zinc finger protein multitype 1 |
| Protein Family: | Zinc finger protein |
| UniProt Gene Name: | ZFPM1 |
| UniProt Entry Name: | FOG1_HUMAN |