Anti-XPO6 Antibody (CAB10401)
- SKU:
- CAB10401
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-XPO6 Antibody |
| 抗体コード: | CAB10401 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 290-530 of human XPO6 (NP_055986.1). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | Jurkat, Mouse testis, Mouse brain |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 290-530 of human XPO6 (NP_055986.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | ASVN GSSQ NCVS GQER GRLG VLAM SCIN ELMS KNCV PMEF EEYL LRMF QQTF YLLQ KITK DNNA HTVK SRLE ELDE SYIE KFTD FLRL FVSV HLRR IESY SQFP VVEF LTLL FKYT FHQP THEG YFSC LDIW TLFL DYLT SKIK SRLG DKEA VLNR YEDA LVLL LTEV LNRI QFRY NQAQ LEEL DDET LDDD QQTE WQRY LRQS LEVV AKVM ELLP THAF STLF PVLQ DNLE VYLG LQQF I |
| 遺伝子ID: | 23214 |
| Uniprot: | Q96QU8 |
| セルラーロケーション: | Cytoplasm, Nucleus |
| 計算された分子量: | 127kDa/128kDa |
| 観察された分子量: | 140kDa |
| 同義語: | XPO6, EXP6, RANBP20 |
| バックグラウンド: | The protein encoded by this gene is a member of the importin-beta family. Members of this family are regulated by the GTPase Ran to mediate transport of cargo across the nuclear envelope. This protein has been shown to mediate nuclear export of profilin-actin complexes. A pseudogene of this gene is located on the long arm of chromosome 14. Alternative splicing results in multiple transcript variants that encode different protein isoforms. |
| UniProt Protein Function: | Exportin-6: a protein of the exportin family. Exportins recruit cargo from the nucleoplasm in the presence of RAN-GTP and form ternary export complexes. These complexes are transported through nuclear pore complexes to the cytoplasm, where GTP is hydrolyzed and the export complex is disassembled. Exportin 6 mediates nuclear export of profilin-actin complexes. |
| UniProt Protein Details: | Protein type:Karyopherin; Nuclear export; Nuclear import Chromosomal Location of Human Ortholog: 16p12.1 Cellular Component: cytoplasm; cytosol; nucleolus; nucleus; plasma membrane Molecular Function:protein binding; protein transporter activity Biological Process: protein export from nucleus |
| NCBI Summary: | The protein encoded by this gene is a member of the importin-beta family. Members of this family are regulated by the GTPase Ran to mediate transport of cargo across the nuclear envelope. This protein has been shown to mediate nuclear export of profilin-actin complexes. A pseudogene of this gene is located on the long arm of chromosome 14. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Aug 2012] |
| UniProt Code: | Q96QU8 |
| NCBI GenInfo Identifier: | 74724278 |
| NCBI Gene ID: | 23214 |
| NCBI Accession: | Q96QU8.1 |
| UniProt Secondary Accession: | Q96QU8,Q2YDX3, Q53G88, Q68G50, Q76N88, Q96CP8, Q9BT21 A1L3W4, D3DWF9, |
| UniProt Related Accession: | Q96QU8 |
| Molecular Weight: | 129kDa |
| NCBI Full Name: | Exportin-6 |
| NCBI Synonym Full Names: | exportin 6 |
| NCBI Official Symbol: | XPO6 |
| NCBI Official Synonym Symbols: | EXP6; RANBP20 |
| NCBI Protein Information: | exportin-6 |
| UniProt Protein Name: | Exportin-6 |
| UniProt Synonym Protein Names: | Ran-binding protein 20 |
| Protein Family: | Exportin |
| UniProt Gene Name: | XPO6 |
 | Western blot analysis of extracts of various cell lines, using XPO6 antibody (CAB10401) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 5s. |
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