Anti-WSB1 Antibody (CAB12195)
- SKU:
- CAB12195
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
| 抗体名: | Anti-WSB1 Antibody |
| 抗体コード: | CAB12195 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 182-421 of human WSB1 (NP_056441.6). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human |
| ポジティブサンプル: | HT-29, A-549, HeLa, HepG2, SGC-7901 |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 182-421 of human WSB1 (NP_056441.6). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | GSLI LVSA SRDK TLRV WDLK DDGN MMKV LRGH QNWV YSCA FSPD SSML CSVG ASKA VFLW NMDK YTMI RKLE GHHH DVVA CDFS PDGA LLAT ASYD TRVY IWDP HNGD ILME FGHL FPPP TPIF AGGA NDRW VRSV SFSH DGLH VASL ADDK MVRF WRID EDYP VQVA PLSN GLCC AFST DGSV LAAG THDG SVYF WATP RQVP SLQH LCRM SIRR VMPT QEVQ ELPI PSKL LEFL SYRI |
| 遺伝子ID: | 26118 |
| Uniprot: | Q9Y6I7 |
| セルラーロケーション: | |
| 計算された分子量: | 24kDa/27kDa/30kDa/47kDa |
| 観察された分子量: | 47kDa |
| 同義語: | WSB1, SWIP1, WSB-1 |
| バックグラウンド: | This gene encodes a member of the WD-protein subfamily. This protein shares a high sequence identity to mouse and chick proteins. It contains several WD-repeats spanning most of the protein and an SOCS box in the C-terminus. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. |
| UniProt Protein Function: | Probable substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes type II iodothyronine deiodinase/DIO2. Confers constitutive instability to HIPK2 through proteasomal degradation. |
| NCBI Summary: | This gene encodes a member of the WD-protein subfamily. This protein shares a high sequence identity to mouse and chick proteins. It contains several WD-repeats spanning most of the protein and an SOCS box in the C-terminus. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9Y6I7 |
| NCBI GenInfo Identifier: | 20532298 |
| NCBI Gene ID: | 26118 |
| NCBI Accession: | Q9Y6I7.1 |
| UniProt Secondary Accession: | Q9Y6I7,Q9NRB1, Q9UBH9, Q9UG25, Q9UNN6, Q9Y656, |
| UniProt Related Accession: | Q9Y6I7 |
| Molecular Weight: | 47kDa |
| NCBI Full Name: | WD repeat and SOCS box-containing protein 1 |
| NCBI Synonym Full Names: | WD repeat and SOCS box containing 1 |
| NCBI Official Symbol: | WSB1 |
| NCBI Official Synonym Symbols: | SWIP1; WSB-1 |
| NCBI Protein Information: | WD repeat and SOCS box-containing protein 1 |
| UniProt Protein Name: | WD repeat and SOCS box-containing protein 1 |
| UniProt Synonym Protein Names: | SOCS box-containing WD protein SWiP-1 |
| Protein Family: | WD repeat and SOCS box-containing protein |
| UniProt Gene Name: | WSB1 |
 | Western blot analysis of extracts of various cell lines, using WSB1 antibody (CAB12195) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25ug per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (RM00021)._Exposure time: 10s. |
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