Anti-WDR45 Antibody (CAB7581)
- SKU:
- CAB7581
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Autophagy
Frequently bought together:
Description
| 抗体名: | Anti-WDR45 Antibody |
| 抗体コード: | CAB7581 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IF |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-360 of human WDR45 (NP_001025067.1). |
| 申し込み: | WB IF |
| 推奨希釈: | WB 1:500 - 1:2000 IF 1:50 - 1:100 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-360 of human WDR45 (NP_001025067.1). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MTQQ PLRG VTSL RFNQ DQSC FCCA METG VRIY NVEP LMEK GHLD HEQV GSMG LVEM LHRS NLLA LVGG GSSP KFSE ISVL IWDD AREG KDSK EKLV LEFT FTKP VLSV RMRH DKIV IVLK NRIY VYSF PDNP RKLF EFDT RDNP KGLC DLCP SLEK QLLV FPGH KCGS LQLV DLAS TKPG TSSA PFTI NAHQ SDIA CVSL NQPG TVVA SASQ KGTL IRLF DTQS KEKL VELR RGTD PATL YCIN FSHD SSFL CASS DKGT VHIF ALKD TRLN RRSA LARV GKVG PMIG QYVD SQWS LASF TVPA ESAC ICAF GRNT SKNV NSVI AICV DGTF HKYV FTPD GNCN REAF DVYL DICD DDDF |
| 遺伝子ID: | 11152 |
| Uniprot: | Q9Y484 |
| セルラーロケーション: | |
| 計算された分子量: | 39kDa/41kDa |
| 観察された分子量: | Refer to figures |
| 同義語: | WDR45, JM5, NBIA4, NBIA5, WDRX1, WIPI-4, WIPI4 |
| バックグラウンド: | This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene has a pseudogene at chromosome 4q31.3. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity and full-length nature of some variants have not been determined. |
| UniProt Protein Function: | WDR45: a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene has a pseudogene at chromosome 4q31.3. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity and full-length nature of some variants have not been determined. [provided by RefSeq, Jul 2008] |
| UniProt Protein Details: | Protein type:Autophagy Chromosomal Location of Human Ortholog: Xp11.23 Cellular Component: cytosol; extrinsic to membrane; pre-autophagosomal structure membrane Molecular Function:phosphatidylinositol 3-phosphate binding Biological Process: autophagic vacuole formation; autophagy; mitochondrion degradation; protein amino acid lipidation Disease: Neurodegeneration With Brain Iron Accumulation 5 |
| NCBI Summary: | This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene has a pseudogene at chromosome 4q31.3. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity and full-length nature of some variants have not been determined. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q9Y484 |
| NCBI GenInfo Identifier: | 74762056 |
| NCBI Gene ID: | 11152 |
| NCBI Accession: | Q9Y484.1 |
| UniProt Secondary Accession: | Q9Y484,Q5MNZ5, Q6IBS7, Q6NT94, Q96H03, A6NGH5, B7WPI2 |
| UniProt Related Accession: | Q9Y484 |
| Molecular Weight: | 39,939 Da |
| NCBI Full Name: | WD repeat domain phosphoinositide-interacting protein 4 |
| NCBI Synonym Full Names: | WD repeat domain 45 |
| NCBI Official Symbol: | WDR45 |
| NCBI Official Synonym Symbols: | JM5; NBIA4; NBIA5; WDRX1; WIPI4; WIPI-4 |
| NCBI Protein Information: | WD repeat domain phosphoinositide-interacting protein 4 |
| UniProt Protein Name: | WD repeat domain phosphoinositide-interacting protein 4 |
| UniProt Synonym Protein Names: | WD repeat-containing protein 45 |
| Protein Family: | WD repeat domain phosphoinositide-interacting protein |
| UniProt Gene Name: | WDR45 |
| UniProt Entry Name: | WIPI4_HUMAN |
 | Immunofluorescence analysis of A549 cells using WDR45 antibody (CAB7581). Blue: DAPI for nuclear staining. |
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