Anti-WDHD1 Antibody (CAB15396)
- SKU:
- CAB15396
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | Anti-WDHD1 Antibody |
抗体コード: | CAB15396 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB IHC IF |
反応性: | Human, Rat |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 830-1129 of human WDHD1 (NP_009017.1). |
申し込み: | WB IHC IF |
推奨希釈: | WB 1:200 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 |
反応性: | Human, Rat |
ポジティブサンプル: | LO2, U-251MG, A-431, HeLa, Jurkat |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 830-1129 of human WDHD1 (NP_009017.1). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | EEEE EEDF RKKL NAGY SNTA TEWS QPRF RNQV EEDA EDSG EADD EEKP EIHK PGQN SFSK STNS SDVS AKSG AVTF SSQG RVNP FKVS ASSK EPAM SMNS ARST NILD NMGK SSKK STAL SRTT NNEK SPII KPLI PKPK PKQA SAAS YFQK RNSQ TNKT EEVK EENL KNVL SETP AICP PQNT ENQR PKTG FQMW LEEN RSNI LSDN PDFS DEAD IIKE GMIR FRVL STEE RKVW ANKA KGET ASEG TEAK KRKR VVDE SDET ENQE EKAK ENLN LSKK QKPL DFST NQKL SAFA FKQE |
遺伝子ID: | 11169 |
Uniprot: | O75717 |
セルラーロケーション: | Nucleus, nucleoplasm |
計算された分子量: | 112kDa/125kDa |
観察された分子量: | 135kDa |
同義語: | WDHD1, AND-1, AND1, CHTF4, CTF4 |
バックグラウンド: | The protein encoded by this gene contains multiple N-terminal WD40 domains and a C-terminal high mobility group (HMG) box. WD40 domains are found in a variety of eukaryotic proteins and may function as adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly. HMG boxes are found in many eukaryotic proteins involved in chromatin assembly, transcription and replication. Alternative splicing results in two transcript variants encoding different isoforms. |
UniProt Protein Function: | WDHD1: Acts as a replication initiation factor that brings together the MCM2-7 helicase and the DNA polymerase alpha/primase complex in order to initiate DNA replication. |
UniProt Protein Details: | Protein type:DNA-binding Chromosomal Location of Human Ortholog: 14q22.2 Cellular Component: nucleoplasm; cytoplasm; chromosome, pericentric region Molecular Function:protein binding; DNA binding; RNA binding; chromatin binding Biological Process: RNA processing; regulation of chromosome organization and biogenesis |
NCBI Summary: | The protein encoded by this gene contains multiple N-terminal WD40 domains and a C-terminal high mobility group (HMG) box. WD40 domains are found in a variety of eukaryotic proteins and may function as adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly. HMG boxes are found in many eukaryotic proteins involved in chromatin assembly, transcription and replication. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] |
UniProt Code: | O75717 |
NCBI GenInfo Identifier: | 5901892 |
NCBI Gene ID: | 11169 |
NCBI Accession: | NP_009017.1 |
UniProt Related Accession: | O75717 |
Molecular Weight: | 135kDa |
NCBI Full Name: | WD repeat and HMG-box DNA-binding protein 1 isoform 1 |
NCBI Synonym Full Names: | WD repeat and HMG-box DNA binding protein 1 |
NCBI Official Symbol: | WDHD1 |
NCBI Official Synonym Symbols: | AND1; CTF4; AND-1; CHTF4 |
NCBI Protein Information: | WD repeat and HMG-box DNA-binding protein 1 |
UniProt Protein Name: | WD repeat and HMG-box DNA-binding protein 1 |
UniProt Synonym Protein Names: | Acidic nucleoplasmic DNA-binding protein 1; And-1 |
Protein Family: | WD repeat and HMG-box DNA-binding protein |
UniProt Gene Name: | WDHD1 |
UniProt Entry Name: | WDHD1_HUMAN |
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