Anti-WBSCR16 Antibody (CAB14330)
- SKU:
- CAB14330
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-WBSCR16 Antibody |
| 抗体コード: | CAB14330 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human, Mouse, Rat |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human WBSCR16 (NP_110425.2). |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:2000 |
| 反応性: | Human, Mouse, Rat |
| ポジティブサンプル: | Raji, HeLa, LO2, Mouse liver, Rat liver |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human WBSCR16 (NP_110425.2). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | MALV ALVA GARL GRRL SGPG LGRG HWTA AGRS RSRR EAAE AEAE VPVV QYVG ERAA RADR VFVW GFSF SGAL GVPS FVVP SSGP GPRA GARP RRRI QPVP YRLE LDQK ISSA ACGY GFTL LSSK TADV TKVW GMGL NKDS QLGF HRSR KDKT RGYE YVLE PSPV SLPL DRPQ ETRV LQVS CGRA HSLV LTDR EGVF SMGN NSYG QCGR KVVE NEIY SESH RVHR MQDF DG |
| 遺伝子ID: | 81554 |
| Uniprot: | Q96I51 |
| セルラーロケーション: | |
| 計算された分子量: | 38kDa/48kDa/49kDa |
| 観察された分子量: | 50kDa |
| 同義語: | RCC1L, WBSCR16, RCC1 like |
| バックグラウンド: | This gene encodes a protein containing regulator of chromosome condensation 1-like repeats. The encoded protein may function as a guanine nucleotide exchange factor. This gene is located in a region of chromosome 7 that is deleted in Williams-Beuren syndrome, a multisystem developmental disorder. Alternative splicing results in multiple transcript variants. |
| UniProt Protein Function: | WBSCR16: a guanine-nucleotide exchange factor (GEF) factor for Ran, a nuclear GTP-binding protein. Its interaction with Ran probably plays an important role in the regulation of gene expression. Deleted in Williams syndrome, a multisystem developmental disorder. Contains six regulator of chromosome condensation (RCC1) domains. |
| UniProt Protein Details: | Protein type:Mitochondrial; GEFs, Ras; GEFs Chromosomal Location of Human Ortholog: 7q11.23 Disease: Williams-beuren Syndrome |
| NCBI Summary: | This gene encodes a protein containing regulator of chromosome condensation 1-like repeats. The encoded protein may function as a guanine nucleotide exchange factor. This gene is located in a region of chromosome 7 that is deleted in Williams-Beuren syndrome, a multisystem developmental disorder. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] |
| UniProt Code: | Q96I51 |
| NCBI GenInfo Identifier: | 116242843 |
| NCBI Gene ID: | 81554 |
| NCBI Accession: | Q96I51.2 |
| UniProt Secondary Accession: | Q96I51,Q548B1, Q8IW88, Q8N572, Q9H0G7, D3DXK0, F5GX55 F5H6C7, |
| UniProt Related Accession: | Q96I51 |
| Molecular Weight: | 48,761 Da |
| NCBI Full Name: | Williams-Beuren syndrome chromosomal region 16 protein |
| NCBI Synonym Full Names: | RCC1 like |
| NCBI Official Symbol: | RCC1L |
| NCBI Official Synonym Symbols: | WBSCR16 |
| NCBI Protein Information: | Williams-Beuren syndrome chromosomal region 16 protein |
| UniProt Protein Name: | Williams-Beuren syndrome chromosomal region 16 protein |
| UniProt Synonym Protein Names: | RCC1-like G exchanging factor-like protein |
| UniProt Gene Name: | WBSCR16 |
| UniProt Entry Name: | WBS16_HUMAN |
 | Western blot analysis of extracts of various cell lines, using WBSCR16 antibody (CAB14330) at 1:3000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s. |
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