Anti-VPS51 Antibody (CAB15651)
- SKU:
- CAB15651
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
抗体名: | Anti-VPS51 Antibody |
抗体コード: | CAB15651 |
抗体サイズ: | 20uL, 50uL, 100uL |
申し込み: | WB |
反応性: | Human |
宿主種: | Rabbit |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human VPS51 (NP_037397.2). |
申し込み: | WB |
推奨希釈: | WB 1:500 - 1:2000 |
反応性: | Human |
ポジティブサンプル: | A-549 |
免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human VPS51 (NP_037397.2). |
精製方法: | Affinity purification |
ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
アイソタイプ: | IgG |
順序: | MAAA AAAG PSPG SGPG DSPE GPEG EAPE RRRK AHGM LKLY YGLS EGEA AGRP AGPD PLDP TDLN GAHF DPEV YLDK LRRE CPLA QLMD SETD MVRQ IRAL DSDM QTLV YENY NKFI SATD TIRK MKND FRKM EDEM DRLA TNMA VITD FSAR ISAT LQDR HERI TKLA GVHA LLRK LQFL FELP SRLT KCVE LGAY GQAV RYQG RAQA VLQQ YQHL PSFR AIQD DCQV ITAR LAQQ LRQR FREG GSGA PEQA ECVE LLLA |
遺伝子ID: | 738 |
Uniprot: | Q9UID3 |
セルラーロケーション: | Golgi apparatus, Recycling endosome, trans-Golgi network |
計算された分子量: | 72kDa/86kDa |
観察された分子量: | 100kDa |
同義語: | VPS51, ANG2, ANG3, C11orf2, C11orf3, FFR |
バックグラウンド: | This gene encodes a member of the vacuolar protein sorting-associated protein 51 family. The encoded protein is a component of the Golgi-associated retrograde protein complex which acts as a tethering factor for carriers in retrograde transport from the early and late endosomes to the trans-Golgi network. Alternative splicing results in multiple transcript variants. |
UniProt Protein Function: | Acts as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). The GARP complex is required for the maintenance of protein retrieval from endosomes to the TGN, acid hydrolase sorting, lysosome function, endosomal cholesterol traffic and autophagy. VPS51 participates in retrograde transport of acid hydrolase receptors, likely by promoting tethering and SNARE-dependent fusion of endosome-derived carriers to the TGN (PubMed:20685960). Acts as component of the EARP complex that is involved in endocytic recycling. The EARP complex associates with Rab4-positive endosomes and promotes recycling of internalized transferrin receptor (TFRC) to the plasma membrane (PubMed:25799061). |
NCBI Summary: | This gene encodes a member of the vacuolar protein sorting-associated protein 51 family. The encoded protein is a component of the Golgi-associated retrograde protein complex which acts as a tethering factor for carriers in retrograde transport from the early and late endosomes to the trans-Golgi network. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012] |
UniProt Code: | Q9UID3 |
NCBI GenInfo Identifier: | 8393009 |
NCBI Gene ID: | 738 |
NCBI Accession: | NP_037397.2 |
UniProt Secondary Accession: | Q9UID3,Q6PJV5, Q7L8A6, Q8WZ35, Q96DF4, Q96GR3, |
UniProt Related Accession: | Q9UID3 |
Molecular Weight: | 72,655 Da |
NCBI Full Name: | vacuolar protein sorting-associated protein 51 homolog |
NCBI Synonym Full Names: | VPS51, GARP complex subunit |
NCBI Official Symbol: | VPS51 |
NCBI Official Synonym Symbols: | FFR; ANG2; ANG3; C11orf2; C11orf3 |
NCBI Protein Information: | vacuolar protein sorting-associated protein 51 homolog |
UniProt Protein Name: | Vacuolar protein sorting-associated protein 51 homolog |
UniProt Synonym Protein Names: | Another new gene 2 protein; Protein fat-free homolog |
UniProt Gene Name: | VPS51 |
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