Anti-VPS45 Antibody (CAB17941)
- SKU:
- CAB17941
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
Frequently bought together:
Description
| 抗体名: | Anti-VPS45 Antibody |
| 抗体コード: | CAB17941 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB |
| 反応性: | Human |
| 宿主種: | Rabbit |
| 免疫原: | A synthetic Peptide of human VPS45 |
| 申し込み: | WB |
| 推奨希釈: | WB 1:500 - 1:1000 |
| 反応性: | Human |
| ポジティブサンプル: |
| 免疫原: | A synthetic Peptide of human VPS45 |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | Email for sequence |
| 遺伝子ID: | 11311 |
| Uniprot: | Q9NRW7 |
| セルラーロケーション: | Endosome membrane, Golgi apparatus membrane, Peripheral membrane protein |
| 計算された分子量: | 61kDa/65kDa |
| 観察された分子量: | Refer to figures |
| 同義語: | VPS45, H1, H1VPS45, SCN5, VPS45A, VPS45B, VPS54A, VSP45, VSP45A |
| バックグラウンド: | Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene is a member of the Sec1 domain family, and shows a high degree of sequence similarity to mouse, rat and yeast Vps45. The exact function of this gene is not known, but its high expression in peripheral blood mononuclear cells suggests a role in trafficking proteins, including inflammatory mediators. Multiple alternatively spliced transcript variants have been found for this gene. |
| UniProt Protein Function: | VPS45A: May play a role in vesicle-mediated protein trafficking from the Golgi stack through the trans-Golgi network. Belongs to the STXBP/unc-18/SEC1 family. |
| UniProt Protein Details: | Protein type:Vesicle Chromosomal Location of Human Ortholog: 1q21.2 Cellular Component: Golgi membrane; Golgi apparatus; integral to membrane; endosome membrane Biological Process: intracellular protein transport; blood coagulation; vesicle docking during exocytosis Disease: Neutropenia, Severe Congenital, 5, Autosomal Recessive |
| NCBI Summary: | Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene is a member of the Sec1 domain family, and shows a high degree of sequence similarity to mouse, rat and yeast Vps45. The exact function of this gene is not known, but its high expression in peripheral blood mononuclear cells suggests a role in trafficking proteins, including inflammatory mediators. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2013] |
| UniProt Code: | Q9NRW7 |
| NCBI GenInfo Identifier: | 23396937 |
| NCBI Gene ID: | 11311 |
| NCBI Accession: | Q9NRW7.1 |
| UniProt Secondary Accession: | Q9NRW7,Q15715, Q53FR8, Q5T4P6, Q9Y4Z6, D3DUZ9, F5H8K1 |
| UniProt Related Accession: | Q9NRW7 |
| Molecular Weight: | 570 |
| NCBI Full Name: | Vacuolar protein sorting-associated protein 45 |
| NCBI Synonym Full Names: | vacuolar protein sorting 45 homolog (S. cerevisiae) |
| NCBI Official Symbol: | VPS45 |
| NCBI Official Synonym Symbols: | H1; SCN5; VSP45; VPS45A; VPS45B; VPS54A; VSP45A; H1VPS45 |
| NCBI Protein Information: | vacuolar protein sorting-associated protein 45; hlVps45; vacuolar protein sorting 45A; leucocyte vacuolar protein sorting 45 |
| UniProt Protein Name: | Vacuolar protein sorting-associated protein 45 |
| Protein Family: | Vacuolar protein sorting-associated protein |
| UniProt Gene Name: | VPS45 |
| UniProt Entry Name: | VPS45_HUMAN |