Anti-VPS33B Antibody (CAB8799)
- SKU:
- CAB8799
- Product type:
- Antibody
- Application:
- WB
- Application:
- IF
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Frequently bought together:
Description
| 抗体名: | Anti-VPS33B Antibody |
| 抗体コード: | CAB8799 |
| 抗体サイズ: | 20uL, 50uL, 100uL |
| 申し込み: | WB IF |
| 反応性: | Human, Mouse |
| 宿主種: | Rabbit |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 348-617 of human VPS33B (NP_061138.3). |
| 申し込み: | WB IF |
| 推奨希釈: | WB 1:1000 - 1:2000 IF 1:50 - 1:200 |
| 反応性: | Human, Mouse |
| ポジティブサンプル: | A-549, MCF7, DU145 |
| 免疫原: | Recombinant fusion protein containing a sequence corresponding to amino acids 348-617 of human VPS33B (NP_061138.3). |
| 精製方法: | Affinity purification |
| ストレージバッファ: | Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| アイソタイプ: | IgG |
| 順序: | CESI MKKK TKQD FQEL IKTE HALL EGFN IRES TSYI EEHI DRQV SPIE SLRL MCLL SITE NGLI PKDY RSLK TQYL QSYG PEHL LTFS NLRR AGLL TEQA PGDT LTAV ESKV SKLV TDKA AGKI TDAF SSLA KRSN FRAI SKKL NLIP RVDG EYDL KVPR DMAY VFGG AYVP LSCR IIEQ VLER RSWQ GLDE VVRL LNCS DFAF TDMT KEDK ASSE SLRL ILVV FLGG CTFS EISA LRFL GREK GYRF IFLT TAVT NSAR LMEA MSEV KA |
| 遺伝子ID: | 26276 |
| Uniprot: | Q9H267 |
| セルラーロケーション: | Cytoplasmic side, Cytoplasmic vesicle, Early endosome, Late endosome membrane, Lysosome membrane, Peripheral membrane protein, Recycling endosome, clathrin-coated vesicle |
| 計算された分子量: | 60kDa/70kDa |
| 観察された分子量: | 62kDa |
| 同義語: | VPS33B |
| バックグラウンド: | Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene is a member of the Sec-1 domain family, and encodes the human ortholog of rat Vps33b which is homologous to the yeast class C Vps33 protein. The mammalian class C vacuolar protein sorting proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway. Mutations in this gene are associated with arthrogryposis-renal dysfunction-cholestasis syndrome. Alternative splicing results in multiple transcript variants. |
| UniProt Code: | Q9H267 |
| NCBI GenInfo Identifier: | 119829191 |
| NCBI Gene ID: | |
| NCBI Accession: | NP_061138 |
| Molecular Weight: | 60kDa |
| NCBI Full Name: | vacuolar protein sorting-associated protein 33B isoform 1 |
| UniProt Protein Name: | Vacuolar protein sorting-associated protein 33B |
| Protein Family: | Vacuolar protein sorting-associated protein |
| UniProt Gene Name: | VPS33B |
| UniProt Entry Name: | VP33B_HUMAN |
 | Western blot analysis of extracts of various cell lines, using VPS33B antibody (CAB8799) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 1s. |
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